Professor Evangelos J. Giamarellos-Bourboulis is Professor of Internal Medicine and Infectious Diseases at the Medical School of the National and Kapodistrian University of Athens, Greece. He is the founder and director of the Hellenic Institute for the Study of Sepsis, Director of the MSc Programme in Infectious Diseases at the University of Athens, and Supervisor of the Immunology of Infectious Diseases Laboratory and Outpatient Clinic at ATTIKON University General Hospital.
He graduated from the Medical School of the National and Kapodistrian University of Athens in 1994 and obtained his PhD in 1998. He completed his specialization in Internal Medicine in 2001 and subsequently received advanced training in the immunology of infectious diseases at Radboud University Medical Centre in Nijmegen, the Netherlands. He has held the position of Professor of Internal Medicine since 2018.
His principal research interests focus on the pathogenesis and immunology of sepsis, immune dysregulation, immunoparalysis, precision immunotherapy, and the development of targeted therapeutic approaches for severe infections. His research also extends to autoinflammatory diseases, particularly hidradenitis suppurativa, and the immunomodulatory properties of antimicrobial agents.
Professor Giamarellos-Bourboulis has made major contributions to the understanding of sepsis-associated immune dysfunction and the development of personalized immunotherapeutic strategies. He led the SAVE and SAVE-MORE clinical trials, which contributed to the regulatory approval of anakinra for the treatment of COVID-19 pneumonia. He also designed and coordinated the ImmunoSep clinical trial, investigating precision immunotherapy based on distinct immune dysfunction phenotypes in sepsis.
His scientific work has contributed to the recognition of hidradenitis suppurativa as an autoinflammatory disorder and to the clinical development of biological therapies for this condition. He has served as principal investigator and coordinator in numerous international multicentre clinical trials addressing sepsis, severe infections, COVID-19 and immune-mediated diseases.
He has served as President of the European Sepsis Alliance, is a member of the Board of the Global Sepsis Alliance, President of the Hellenic Society of Chemotherapy, and coordinator of the Hellenic Sepsis Study Group. He has received several national and international scientific distinctions, including the Young Investigator Research Award of the European Society of Clinical Microbiology and Infectious Diseases in 2009.
Scientific output: Professor Giamarellos-Bourboulis has authored 627 peer-reviewed scientific publications, with 50,258 citations and an h-index of 102.
Professor Giamarellos-Bourboulis has designed and conducted numerous investigator-initiated clinical studies, including EMBRACE, ImmunoSep, ACCESS, SAVE-MORE, SAVE, ACHIEVE, ESCAPE, PROVIDE, INCLASS, ACTIVATE, INTELLIGENCE, SPECIFY.
His scientific and clinical activities continue to focus on translating advances in immunology and precision medicine into improved diagnosis and treatment of patients with sepsis and other severe inflammatory conditions.

He is an internist and infectious diseases consultant. He went through all the levels of hierarchy at the University of Patras where he became Professor of Internal Medicine and Infectious Diseases. During the period 2006-2011 he served as chairman of the Department of Internal Medicine and of Infectious Diseases of the Rion University Hospital of the University of Patras. His main research interests are the pharmacology of newer antimicrobials and the pathophysiology of sepsis. He has 87 publications in peer-reviewed international journals and h-index 31.

She graduated from the National and Kapodistrian University of Athens Medical School in 1969 when she also completed her PhD in 1976 on the pharmacokinetic properties of 2nd generation cephalosporins. She was trained in Infectious Diseases in London in 1980. She went through all ranks of hierarchy of the National and Kapodistrian University of Athens Medical School as lecturer in 1979, Assistant Professor in 1989, Associate Professor in 2000 and Professor of Internal Medicine and Infectious Diseases in 2011. She is currently Emeritus Professor of Internal Medicine and Infectious Diseases of the National and Kapodistrian University of Athens. Her main research interests are the pharmacokinetics of newer antimicrobials and the management of orthopedic infections with the use of elution systems. She has published 82 peer-reviewed articles in international journals with more than 1,000 citations.

She graduated from the National and Kapodistrian University of Athens Medical School in 1996, where she also completed her PhD in 2006 on the in vivo effect of arachidonic acid on the management of experimental infections by multidrug-resistant Pseudomonas aeruginosa. She finished her training in internal medicine in Laikon Athens Hospital in 2003 and she specialized in the immunology of infectious disease at the Radboud University Nijmegen, The Netherlands in 2006-2007. She also received training in the management of Diabetes Mellitus in 2009-2010 at the Out-Patients Department of Diabetes of the ATTIKON University Hospital. She is currently Consultant of Internal Medicine at ATTIKON University Hospital. Her research interests include the pathogenesis of sepsis with emphasis on biological therapies. She has published 36 peer-reviewed articles in international scientific journals.

He is an internist and infectious diseases consultant. He went through all the levels of hierarchy at the University of Patras where he is since 2004 Professor of Internal Medicine and Infectious Diseases. From 2011 to 2020 he served as chairman of the Department of Internal Medicine and of Infectious Diseases of the Rion University Hospital of the University of Patras. His main research interests are the pathophysiology of sepsis with emphasis on the immunoparalysis of sepsis and the management of chronic hepatitis C. He has 252 publications in peer-reviewed international journals and h-index 57. Ηe is the coordinator of the Hellenic Sepsis Study Group since 2006.