JAMA
Original Investigation
Precision Immunotherapy to Improve Sepsis Outcomes: The ImmunoSep Randomized Clinical Trial
Published: December 8, 2025
CCR Down Under 2025, December 9th & 10th, Melbourne:
The Best Critical Care Trials in the World
Professor Evangelos J. Giamarellos-Bourboulis presented the ImmunoSep trial, one of the top clinical trials in the world marking a milestone for Greece’s presence in international medicine.
THE LANCET
Respiratory Medicine
Clarithromycin for early anti-inflammatory responses in community-acquired pneumonia in Greece (ACCESS): a randomised, double-blind, placebo-controlled trial
Published:January 03, 2024
Lisbon, Portugal | October 10–14, 2026
Hellenic Institute for the Study of Sepsis at ESICM LIVES 2026
Highlights from the Hellenic Institute for the Study of Sepsis at ESICM LIVES 2026 in Lisbon, featuring research on immunomodulation and precision immunotherapy.
The Hellenic Institute for the Study of Sepsis participated in ESICM LIVES 2026, presenting research on personalized immunomodulation, precision immunotherapy, and the EMBRACE trial. The congress provided an opportunity to share advances in sepsis research and engage in international scientific exchange.
Latest publications
Our Founding History

At the dawn of the financial crisis in Greece, a group of 14 researchers and clinicians realized the need to struggle to maintain a high level of research and education for sepsis and systemic inflammation that are the main disorders leading to death in our world. This group inaugurated in July 2010 the Hellenic Institute for the Study of Sepsis (HISS), a nonprofit, non-commercial organization.







