Support of publications

Based on its mission, the Hellenic Institute for the Study of Sepsis is supporting three types of publications of manuscripts:
a) manuscripts of the Hellenic Sepsis Study Group;
b) manuscripts on hidradenitis suppurativa; and
c) manuscripts on sepsis.
Support is provided to both pre-clinical and clinical studies and involves the expenses for personnel and consumables.
A list of supported publications is provided below.

The majority of manuscripts published by the Hellenic Sepsis Study Group, are coming from the registry of patients that has started in 2006 and that has been approved by the Ethics Committees of the hospitals (details on Ethical Approval are provided on the Methods section of each manuscript).

The manuscripts are classified by research topic. When the copyright belongs to the authors the entire pdf is given for free or else the manuscript is linked to the PubMed respective site.

Our Library

Early treatment of COVID-19 with anakinra guided by soluble urokinase plasminogen receptor plasma levels: a double-blind, randomized controlled phase 3 trial
Publication in Nature Medicine
From the related study SAVE-MORE to the approval of the study drug by EMA and FDA
More details
9March, 2023

Presepsin as a diagnostic and prognostic biomarker of severe bacterial infections and COVID‑19

By |March 9th, 2023|Categories: Biomarkers, Publications|Tags: |

 Evdoxia Kyriazopoulou, Konstantinos Leventogiannis, Georgios Tavoulareas, Efstratios Mainas, Konstantinos Toutouzas, Christos Mathas, Athanassios Prekates, Vissaria Sakka, Periklis Panagopoulos, Konstantinos Syrigos & Evangelos J. Giamarellos-Bourboulis Scientific Reports 13, Article number: 3814 (2023) DOI: 10.1038/s41598-023-30807-5Download pdf 🡇 Funding  The study was funded in part by the FrameWork 7 project HemoSpec (Grant 611682) and in part

10February, 2023

Case report: The devil was hidden in the mastocytes – an unusually fulminant case of indolent systemic mastocytosis in a 45-year-old patient, missed for almost 20 years

By |February 10th, 2023|Categories: Epidemiology, Publications|

Aristeidis E. Boukouris, Ioannis Michelakis, Dionysios Metaxas, Gianna Karapati, George Kanellis, Athina Lioni, Vasiliki Tzavara Frontiers Immunology, 14:1134587 DOI: 10.1111/cea.12318Download pdf 🡇 Funding This study was funded by the Hellenic Institute for the Study of Sepsis. Keywords: Case report

27December, 2022

Efficacy and safety of early soluble urokinase plasminogen receptor plasma-guided anakinra treatment of COVID-19 pneumonia: A subgroup analysis of the SAVE-MORE randomised trial

By |December 27th, 2022|Categories: Publications, Therapeutics|Tags: , , , |

Karolina Akinosoglou, Antigone Kotsaki, Ioanna-Maria Gounaridi, Eirini Christaki, Simeon Metallidis, Georgios Adamis, Archontoula Fragkou, Massimo Fantoni, Aggeliki Rapti, Ioannis Kalomenidis, Georgios Chrysos, Gloria Boni, Ilias Kainis, Zoi Alexiou, Francesco Castelli, Francesco Saverio Serino, Petros Bakakos, Emanuele Nicastri, Vassiliki Tzavara, Asimina Safarika, Sofia Ioannou, Lorenzo Dagna, Katerina Dimakou, Glykeria Tzatzagou, Maria Chini, Matteo Bassetti, Vasileios

27December, 2022

Oral minocycline plus rifampicin versus oral linezolid for complicated skin and skin structure infections caused by methicillin-resistant Staphylococcus aureus: The AIDA open label, randomized, controlled Phase 4 trial

By |December 27th, 2022|Categories: Publications, Therapeutics|Tags: , |

Antigone Kotsaki, Nikolaos Tziolos, Theano Kontopoulou, Ioannis M. Koutelidakis, Styliani Symbardi, Vaughan Reed, Miriam O’Hare, Zoi Alexiou, Helen Sambatakou, Konstantinos Toutouzas, Karolina Akinosoglou, Malvina Lada, Evangelos J. Giamarellos-Bourboulis, and Alasdair MacGowan eClinicalMedicine Volume 56, 101790, February 01, 2023 DOI: 10.1016/j.eclinm.2022.101790Download pdf 🡇 Funding The EU Seventh Research Framework Programme. Keywords: Minocycline;

21December, 2022

ImmunoSep (Personalised Immunotherapy in Sepsis) international double-blind, double-dummy, placebo-controlled randomised clinical trial: study protocol

By |December 21st, 2022|Categories: Publications, Therapeutics|Tags: , , |

Antigone Kotsaki, Peter Pickkers , Michael Bauer, Thierry Calandra, Mihaela Lupse, W Joost Wiersinga, Sylvain Meylan , Frank Bloos, Tom van der Poll, Marleen A Slim , Niels van Mourik, Marcella C A Müller, Lonneke van Vught,8 Alexander P J Vlaar, Aline de Nooijer, Lieke Bakkerus, Sebastian Weis, Nikolaos Antonakos, Mihai G Netea, Evangelos

19December, 2022

Interferon gamma-induced protein 10 (IP-10) for the early prognosis of the risk for severe respiratory failure and death in COVID-19 pneumonia

By |December 19th, 2022|Categories: Pathogenesis, Publications|Tags: , , |

Charilaos Samaras, Evdoxia Kyriazopoulou, Garyfallia Poulakou, Eran Reiner, Maria Kosmidou, Ioanna Karanika, Vasileios Petrakis, George Adamis, Nikolaos K. Gatselis, Archontoula Fragkou, Aggeliki Rapti, Eleonora Taddei, Ioannis Kalomenidis, George Chrysos, Giulia Bertoli, Ilias Kainis, Zoi Alexiou, Francesco Castelli, Francesco Saverio Serino, Petros Bakakos, Emanuele Nicastri, Vassiliki Tzavara, Evangelos Kostis, Lorenzo Dagna, Sofia Koukidou, Glykeria Tzatzagou,

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