Completed study
Official Study Title
a SUPar guided doublE-blind Randomized clinical trial of Initiation Of antibiotics foR presumed infection at the emergency department
Brief Description
SUPERIOR is a randomized clinical trial aiming to evaluate suPAR – guided medical intervention, consisting of early antibiotic administration at the emergency room for presumed infection and sepsis and evaluate the impact of this intervention to the patients’ final outcome.
Details
Status: Completed
Study Type: Interventional (Clinical Trial)
Study phase: IV
Study sites: 5 sites in Greece
Estimated enrolment: 220 participants
ClinicalTrials.gov Identifier: NCT03717350
EudraCT number: 2018-001008-13
National Organization for Medicines Approval: IS052-18
National Ethics Committee Approval: 46/18
Study Start: October 2018
Condition/Disease studied: Sepsis
Keywords: biomarkers; suPAR; outcome; antibiotics
Related publications
- Biomarkers in sepsis: can they help improve patient outcome?
Current Opinion in Infectious Diseases 2021 Apr 1;34(2):126-134 - qSOFA combined with suPAR for early risk detection and guidance of antibiotic treatment in the emergency department: a randomized controlled trial
Critical Care volume 28, Article number: 42 (2024)