PROMPT

Completed study

Official Study Title
Prospective Multi-centre Clinical Study to Assess the Clinical Validity of the Heparin Binding Protein Assay to Indicate the Presence and Outcome of Sepsis in Patients With Suspected Infection Following Emergency Department Admission

Brief Description
PROMPT is a non-interventional trial aiming to validate the diagnostic accuracy of Heparin Binding Protein for patients admitted in the emergency department in the diagnosis of sepsis and short-outcome prognosis.

Details
Status: Completed
Study Type: Non-Interventional
Study phase: II
Study sites: 6 sites in Greece
Actual enrolment: 400 participants

ClinicalTrials.gov Identifier: NCT03295825

Study Start: September 2017
Study Completion: September 2018

Condition/Disease studied: Sepsis; Infection
Keywords: Heparin binding protein; Mortality

Related publications

• A 29-mRNA host response test from blood accurately distinguishes bacterial and viral infections among emergency department patients
  Intensive Care Medicine Experimental 2021 Jun 18;9(1):31
• A 29-MRNA HOST RESPONSE WHOLE-BLOOD SIGNATURE IMPROVES PREDICTION OF 28-DAY MORTALITY AND 7-DAY INTENSIVE CARE UNIT CARE IN ADULTS PRESENTING TO THE EMERGENCY DEPARTMENT WITH SUSPECTED ACUTE INFECTION AND/OR SEPSIS
  Shock 2022 Sep 1;58(3):224-230