Anna C Aschenbrenner, Maria Mouktaroudi, Benjamin Krämer, Marie Oestreich, Nikolaos Antonakos, Melanie Nuesch-Germano, Konstantina Gkizeli, Lorenzo Bonaguro, Nico Reusch, Kevin Baßler, Maria Saridaki, Rainer Knoll, Tal Pecht, Theodore S Kapellos, Sarandia Doulou, Charlotte Kröger, Miriam Herbert, Lisa Holsten, Arik Horne, Ioanna D Gemünd, Nikoletta Rovina, Shobhit Agrawal, Kilian Dahm, Martina van Uelft, Anna Drews, Lena Lenkeit, Niklas Bruse, Jelle Gerretsen, Jannik Gierlich, Matthias Becker, Kristian Händler, Michael Kraut, Heidi Theis, Simachew Mengiste, Elena De Domenico, Jonas Schulte-Schrepping, Lea Seep, Jan Raabe, Christoph Hoffmeister, Michael ToVinh, Verena Keitel, Gereon Rieke, Valentina Talevi, Dirk Skowasch, N Ahmad Aziz, Peter Pickkers, Frank L van de Veerdonk, Mihai G Netea, Joachim L Schultze, Matthijs Kox, Monique M B Breteler, Jacob Nattermann, Antonia Koutsoukou, Evangelos J. Giamarellos-Bourboulis, Thomas Ulas; German COVID- Omics Initiative (DeCOI)
ACA was supported by an intramural grant from the Department of Genomics & Immunoregulation at the LIMES Institute. The work of JLS and MMBB was supported by the German Research Foundation (DFG) under Germany’s Excellence Strategy – EXC2151 – 390873048 as well as by the Diet-Body-Brain Competence Cluster in Nutrition Research funded by the Federal Ministry of Education and Research (grant numbers 01EA1410C and 01EA1809C). JLS was further supported by the DFG under SCHU 950/8-1; GRK 2168, TP11; SFB704, the EU project SYSCID under grant number 733100. MGN was supported by a Spinoza grant of the Netherlands Organisation for Scientific Research and an ERC Advanced Grant (833247). The study was funded in part by the Hellenic Institute for the Study of Sepsis. EJG-B received funding from the FrameWork 7 program HemoSpec and from the Horizon2020 Marie-Curie project European Sepsis Academy (granted to the National and Kapodistrian University of Athens). JN was supported by the DFG (SFB TR57, SPP1937), the DZIF, and the Hector-Foundation (M89).
Keywords: Blood transcriptomics; COVID-19; Co-expression analysis; Drug repurposing; Granulocytes; Molecular disease phenotypes; Neutrophils; Stratification; Transcriptome