Biomarkers

7 February, 2024

qSOFA combined with suPAR for early risk detection and guidance of antibiotic treatment in the emergency department: a randomized controlled trial

2024-02-07T15:45:40+03:00By hiss|Categories: Biomarkers, Publications|Tags: meropenem, qSOFA, Sepsis, suPAR|

Maria Evangelia Adami, Antigone Kotsaki, Nikolaos Antonakos, Efthymia Giannitsioti, Stamatios Chalvatzis, Maria Saridaki, Christina Avgoustou, Karolina Akinosoglou, Konstantina Dakou, Georgia Damoraki, Konstantina Katrini, Panagiotis Koufargyris, Vasileios Lekakis, Antonia Panagaki, Asimina Safarika, Jesper Eugen‐Olsen and Evangelos J. Giamarellos-Bourboulis Critical Care volume 28, Article number: 42 (2024) DOI: 10.1186/s13054-024-04825-2Download pdf 🡇 Funding The

2 February, 2024

Developing a Tool for Differentiation Between Bacterial and Viral Respiratory Infections Using Myxovirus Resistance Protein A and C-Reactive Protein

2024-02-02T13:03:15+03:00By hiss|Categories: Biomarkers, Publications|Tags: CRP, diagnosis, infection|

Konstantina Iliopoulou, Panagiotis Koufargyris, Sarantia Doulou, Elisavet Tasouli, Sokratis Katopodis, Stavroula-Porphyria Chachali, Georgios Schinas, Charalampos Karachalios, Myrto Astriti, Paraskevi Katsaounou, George Chrysos, Theodoros Seferlis, Effrosyni Dimopoulou, Myrto Kollia, Garyphalia Poulakou, Styliani Gerakari, Ilias C. Papanikolaou, Haralampos Milionis, George N. Dalekos, Vasiliki Tzavara, Theano Kontopoulou, Evangelos J. Giamarellos-Bourboulis Infect Dis Ther. 2024 Jan;13(1):105-119 DOI: 10.1007/s40121-023-00901-2Download

5 January, 2024

Association of Vitamin D with Severity and Outcome of COVID-19: Clinical and Experimental Evidence

2024-01-05T14:33:18+03:00By hiss|Categories: Biomarkers, Publications|Tags: ARDS, COVID-19|

Georgios Renieris, Spyros Foutadakis, Theano Andriopoulou, Victoria-Marina Spanou, Dionyssia-Eirini Droggiti, Dionysios Kafousopoulos , Theologia Gkavogianni, Georgia Damoraki, Giannis Vatsellas, Evangelos J. Giamarellos-Bourboulis J Innate Immun (2023) 16 (1): 1–11DOI: 10.1159/000535302Download pdf 🡇 FundingThe study was funded by the Hellenic Institute for the Study of Sepsis. Keywords: Vitamin D; Tumor necrosis factor; Interleukin-6; Interferon gamma;

7 July, 2023

Analysis of inflammatory protein profiles in the circulation of COVID-19 patients identifies patients with severe disease phenotypes

2023-07-07T09:39:43+03:00By hiss|Categories: Biomarkers, Publications|Tags: COVID-19, phenotypes|

Nick Keur, Maria Saridaki, Isis Ricano-Ponce, Mihai G. Netea, Evangelos J. Giamarellos-Bourboulis, Vinod Kumar Respiratory Medicine 2023 Jun 25; 217:107331 DOI: 10.1016/j.rmed.2023.107331Download pdf 🡇 Funding This work was funded by the ZonMw (10430012010002) to VK. The SAVE study was funded by the Hellenic Institute for the Study of Sepsis, Swedish Orphan

9 March, 2023

Presepsin as a diagnostic and prognostic biomarker of severe bacterial infections and COVID‑19

2023-03-09T12:07:30+03:00By hiss|Categories: Biomarkers, Publications|Tags: COVID-19|

Evdoxia Kyriazopoulou, Konstantinos Leventogiannis, Georgios Tavoulareas, Efstratios Mainas, Konstantinos Toutouzas, Christos Mathas, Athanassios Prekates, Vissaria Sakka, Periklis Panagopoulos, Konstantinos Syrigos & Evangelos J. Giamarellos-Bourboulis Scientific Reports 13, Article number: 3814 (2023) DOI: 10.1038/s41598-023-30807-5Download pdf 🡇 Funding The study was funded in part by the FrameWork 7 project HemoSpec (Grant 611682) and in part

1 September, 2021

BioFire® FilmArray® Pneumonia Panel for Severe Lower Respiratory Tract Infections: Subgroup Analysis of a Randomized Clinical Trial

2024-04-01T07:35:21+03:00By hiss|Categories: Biomarkers, Multicenter studies in Greece, Publications|Tags: clinical trial, procalcitonin|

Evdoxia Kyriazopoulou, Athanasios Karageorgos, Lydia Liaskou-Antoniou, Panagiotis Koufargyris, Asimina Safarika, Georgia Damoraki, Vasileios Lekakis, Maria Saridaki, George Adamis, Evangelos J. Giamarellos-Bourboulis Infectious Diseases and Therapy 2021 Sep;10(3):1437-1449 DOI: 10.1007/s40121-021-00459-xDownload pdf 🡇 Funding The PROGRESS trial was supported by grants by the Hellenic Institute for the Study of Sepsis and by bioMérieux, Lyon,

1 July, 2021

Integration of heparin-binding protein and interleukin-6 in the early prediction of respiratory failure and mortality in pneumonia by SARS-CoV-2 (COVID-19)

2024-04-01T07:28:20+03:00By hiss|Categories: Biomarkers, Publications|Tags: COVID-19|

Maria Saridaki, Simeon Metallidis, Sotiria Grigoropoulou, Emmanouil Vrentzos, Malvina Lada, Katerina Argyraki, Olga Tsachouridou, Anna Georgiadou, Anil Vasishta, Evangelos J. Giamarellos-Bourboulis European Journal of Clinical Microbiology & Infectious Diseases 2021 Jul;40(7):1405-1412 DOI: 10.1007/s10096-020-04145-7Download pdf 🡇 Funding The study was funded in part by the Hellenic Institute for the Study of Sepsis and

1 April, 2021

Biomarkers in sepsis: can they help improve patient outcome?

2023-02-16T13:27:11+03:00By hiss|Categories: Biomarkers, Publications|Tags: Sepsis|

Kyriazopoulou Evdoxia, Poulakou Garyfallia, Evangelos J. Giamarellos-Bourboulis eBioMedicine 2016 Apr;6:114-125 DOI: 10.1097/QCO.0000000000000707 View article 🡇 Funding The study was funded by the Hellenic Institute for the Study of Sepsis. Keywords: biomarkers; mortality; multidrug-resistant; procalcitonin; sepsis

1 January, 2021

Diabetes on sepsis outcomes in non-ICU patients: A cohort study and review of the literature

2023-02-16T13:36:16+03:00By hiss|Categories: Biomarkers, Publications|Tags: diabetes, Sepsis|

Karolina Akinosoglou, Georgia Kapsokosta, Maria Mouktaroudi, Nikoletta Rovina, Vassileios Kaldis, Aggelos Stefos, Marina Kontogiorgi, Evangelos J. Giamarellos-Bourboulis, Charalambos Gogos, Hellenic Sepsis Study Group Journal of Diabetes and Its Complications 2021 Jan;35(1):107765 DOI: 10.1016/j.jdiacomp.2020.107765View article 🡇 Funding The works were supported by the BMBF within the framework of the “MetaZIK”/ZIK Septomics Jena (03Z2J521),

19 November, 2020

A novel optical biosensor for the early diagnosis of sepsis and severe Covid-19: the PROUD study

2024-03-29T13:55:21+03:00By hiss|Categories: Biomarkers, Publications|Tags: clinical trial, COVID-19, Sepsis|

Sarantia Doulou, Konstantinos Leventogiannis, Maria Tsilika, Matthew Rodencal, Konstantina Katrini, Nikolaos Antonakos, Miltiades Kyprianou, Emmanouil Karofylakis, Athanassios Karageorgos, Panagiotis Koufargyris, Gennaios Christopoulos, George Kassianidis, Kimon Stamatelopoulos, Robert Newberry, Evangelos J. Giamarellos-Bourboulis BMC Infectious Diseases 2020 Nov 19;20(1):860 DOI: 10.1186/s12879-020-05607-1Download pdf 🡇 Funding The study was funded in part by the Hellenic Institute