Publications

14 October, 2026

Innate immune response in COVID-19 pneumonia during the pandemic: a prospective cohort study

2026-10-14T11:13:57+03:00By hiss|Categories: Publications, Sepsis and severe infections|Tags: CAP, COVID-19, cytokines|

Annals of Intensive Care, Volume 16, 2026

6 April, 2026

Molecular pathways driving clarithromycin benefit in community-acquired pneumonia analysis of the ACCESS randomised trial

2026-10-14T11:51:29+03:00By hiss|Categories: Publications, Therapeutics|Tags: clarithromycin, pneumonia|

EBioMedicine 2026 Apr 3

3 January, 2026

A randomized controlled trial of precision bezlotoxumab treatment for Clostridioides difficile infection

2026-10-14T11:51:59+03:00By hiss|Categories: Publications, Therapeutics|Tags: bezlotoxumab, CDI, microbiome|

Cell Reports Medicine, January 2, 2026

2 January, 2026

Blood biomarker and Raman analysis of leukocytes in the multicenter INTELLIGENCE trials: at the Intensive Care Unit (INTELLIGENCE-1) and the Emergency Department (INTELLIGENCE-2)

2026-10-14T11:52:34+03:00By hiss|Categories: Biomarkers, Publications|Tags: ICU, Sepsis, spetroscopy|

SHOCK, Vol. 65

2 January, 2026

Efficacy of anakinra in reducing progression to organ dysfunction in patients with pneumonia (INSPIRE): a randomised, double-blind, placebo-controlled phase IIa trial

2026-10-14T11:53:05+03:00By hiss|Categories: Biomarkers, Publications, Therapeutics|Tags: Anakinra, mortality, pneumonia, presepsin|

The Lancet Regional Health - Europe 2026

14 December, 2025

Precision Immunotherapy to Improve Sepsis Outcomes: The ImmunoSep Randomized Clinical Trial

2026-10-14T11:53:59+03:00By hiss|Categories: Publications, Sepsis and severe infections, Therapeutics|Tags: Sepsis, Studies on Sepsis and severe infections|

JAMA 2026 Mar 3

23 October, 2025

Hydrogen sulfide to modulate Glycated hemoglobin and gut microbiome in type 2 diabetes mellitus

2026-10-14T11:57:50+03:00By hiss|Categories: Biomarkers, Publications|Tags: diabetes, microbiome|

Metabolism Open, Volume 28, 2025

1 September, 2025

An NGS-assisted diagnostic workflow for culture-independent detection of bloodstream pathogens and prediction of antimicrobial resistances in sepsis

2026-10-14T11:59:12+03:00By hiss|Categories: Biomarkers, Publications|Tags: diagnosis, Sepsis|

Front. Cell. Infect. Microbiol. 15

9 August, 2025

Biomarkers to guide sepsis management

2025-08-22T19:16:30+03:00By hiss|Categories: Biomarkers, Publications|Tags: Sepsis|

Vasiliki Bourika, Evangelia-Areti Rekoumi and Evangelos J. Giamarellos-Bourboulis Ann Intensive Care. 2025 Jul 21;15(1):103 DOI: 10.1186/s13613-025-01524-1Download pdf 🡇 Funding No funding was provided for this manuscript. Keywords: Sepsis, Biomarkers, Guidance, Antibiotics, Fluids, Vasopressors

1 July, 2025

29-mRNA host response signatures for classifcation of bacterial infection, viral infection and disease progression in COVID-19 pneumonia: a post hoc analysis of the SAVE-MORE randomized clinical trial

2025-07-01T22:02:55+03:00By hiss|Categories: Biomarkers, Publications|Tags: COVID-19, infection, pneumonia, Sepsis|

Evdoxia Kyriazopoulou, Antigone Kotsaki, Asimina Safarika, Garyfallia Poulakou, Haralampos Milionis, Simeon Metallidis, Georgios Adamis, Archontoula Fragkou, Aggeliki Rapti, Pierluigi Del Vecchio, Ioannis Kalomenidis, Danae Kitzoglou, Andrea Angheben, Ilias Kainis, Konstantina Iliopoulou, Francesco Saverio Serino, Petros Bakakos, Vassiliki Tzavara, Sofa Ioannou, Lorenzo Dagna, Katerina Dimakou, Glykeria Tzatzagou, Maria Chini, Matteo Bassett, Vasileios Kotsis, George Tsoukalas,