George Dimopoulos, Quirijn de Mast, Nikolaos Markou, Maria Theodorakopoulou, Apostolos Komnos, Maria Mouktaroudi, Mihai G Netea, Themistoklis Spyridopoulos, Rebecca J Verheggen, Jacobien Hoogerwerf, Alexandra Lachana, Frank L van de Veerdonk, Evangelos J. Giamarellos-Bourboulis

Favorable Anakinra Responses in Severe Covid-19 Patients with Secondary Hemophagocytic Lymphohistiocytosis

Cell Host & Microbe 2020 Jul 8;28(1):117-123.e1
DOI 10.1016/j.chom.2020.05.007Download pdf 🡇


The study was funded in part by the Horizon 2020 grant ImmunoSep (#847422) and in part by the Hellenic Institute for the Study of Sepsis. MGN was supported by an ERC Advanced grant (#833247) and a Spinoza grant from the Netherlands Organization for Scientific Research.

Keywords: Anakinra; COVID-19; HScore; SARS-CoV-2; ferritin; hemophagocytic lymphohistocytosis; pneumonia; respiratory function