Michael Bauer, Evangelos J. Giamarellos-Bourboulis, Andreas Kortgen, Eva Möller, Karen Felsmann, Jean Marc Cavaillon, Orlando Guntinas-Lichius, Olivier Rutschmann, Andriy Ruryk, Matthias Kohl, Britta Wlotzka, Stefan Rußwurm, John C Marshall, Konrad Reinhart

A Transcriptomic Biomarker to Quantify Systemic Inflammation in Sepsis – A Prospective Multicenter Phase II Diagnostic Study

eBioMedicine 2016 Apr;6:114-125
DOI: 10.1016/j.ebiom.2016.03.006Download pdf 🡇


The works were supported by the BMBF within the framework of the “MetaZIK”/ZIK Septomics Jena (03Z2J521), the Thuringian Ministry of Education, Science and Art (projects B-309-00014 and A 309-04002), and by Thüringer Aufbaubank (“RNA Score 2007 FE 014”). Part of the study was funded by the Hellenic Institute for the Study of Sepsis.

Keywords: Adaptive immunity; Clinical utility; Host response; Point-of-care; RT-qPCR; Transcriptomic profiling