Nicky Solomonidi, Panayiotis G. Vlachoyiannopoulos, Maria Pappa, Georgia Liantinioti, Sofia Ktena, Evangelos Theotikos, Antonia Elezoglou, Mihai G. Netea, and Evangelos J. Giamarellos-Bourboulis iScience 2023 Aug 19;26(9):107670 DOI: 10.1016/j.isci.2023.107670Download pdf 🡇 Funding The study was supported in part by the Hellenic Institute for the Study of Sepsis and in part by Janssen.
Dimitra Bacharaki, Minas Karagiannis, Panagiotis Giannakopoulos, Evangelos Papachristou, Dimitrios Divanis, Aggeliki Sardeli, Dimitra Petrou, Petros Nikolopoulos, Adamantia Bratsiakou, Vassiliki Zoi, Nikitas Piliouras, Georgia Damoraki, Vassilios Liakopoulos, Dimitrios Goumenos and Evangelos J. Giamarellos-Bourboulis BMC Infectious Diseases (2023) 23:581 DOI: 10.1186/s12879-023-08569-2Download pdf 🡇 Funding The study was funded by the Hellenic Institute for
Ongoing study Official Study Title Safety and efficacy of Anakinra treatment for patients with Persistent REspiratory symptoms post-acute COVID and Immune System activatION: the PRECISION double-blind, randomized clinical trial Brief Description The effect of the drug anakinra in the treatment of long-term complications after COVID-19. The PRECISION is a proof-of-concept, phase II randomized clinical
Evangelos J. Giamarellos-Bourboulis on behalf of the European Sepsis Alliance (ESA), Annelies S. Zinkernagel on behalf of the European Society of Clinical Microbiology and Infectious Diseases (ESCMID), Edoardo De Robertis on behalf of the European Society of Anesthesiology and Intensive Care (ESAIC), Élie Azoulay on behalf of the European Society for Intensive Care Medicine
  Nick Keur, Maria Saridaki, Isis Ricano-Ponce, Mihai G. Netea, Evangelos J. Giamarellos-Bourboulis, Vinod Kumar Respiratory Medicine 2023 Jun 25; 217:107331 DOI: 10.1016/j.rmed.2023.107331Download pdf 🡇 Funding   This work was funded by the ZonMw (10430012010002) to VK. The SAVE study was funded by the Hellenic Institute for the Study of Sepsis, Swedish Orphan
 Evdoxia Kyriazopoulou, Konstantinos Leventogiannis, Georgios Tavoulareas, Efstratios Mainas, Konstantinos Toutouzas, Christos Mathas, Athanassios Prekates, Vissaria Sakka, Periklis Panagopoulos, Konstantinos Syrigos & Evangelos J. Giamarellos-Bourboulis Scientific Reports 13, Article number: 3814 (2023) DOI: 10.1038/s41598-023-30807-5Download pdf 🡇 Funding  The study was funded in part by the FrameWork 7 project HemoSpec (Grant 611682) and in part
Ongoing study Official Study Title A RANDOMIZED PROSPECTIVE CLINICAL TRIAL TO ASSESS PROCALCITONIN-GUIDANCE AND MOLECULAR-GUIDED DIAGNOSIS AS MAINSTAY FOR THERAPY OF SEVERE INFECTIONS (The MODIFY trial) Brief Description The aim of the study is to demonstrate if using a combined strategy of rapid molecular diagnosis with BioFire® FilmArray® Blood Culture Identification 2 Panel and
Aristeidis E. Boukouris, Ioannis Michelakis, Dionysios Metaxas, Gianna Karapati, George Kanellis, Athina Lioni, Vasiliki Tzavara Frontiers Immunology, 14:1134587 DOI: 10.1111/cea.12318Download pdf 🡇 Funding This study was funded by the Hellenic Institute for the Study of Sepsis. Keywords: Case report
Ongoing study Official Study Title Safety and Efficacy of Recombinant Interferon-Gamma 1b (rIFN-Gamma 1b) Given With Standard Therapy in Patients With Candidemia: The HDM-FUN-Candidemia trial Brief Description Invasive fungal infections are an important cause of morbidity and mortality and lead to numerous hospital and ICU admissions. Candidemia is associated with a suppressed immune status
Ongoing study Official Study Title Symptom-guided Anakinra treatment for the Validation of immunE dysfunction persisting for LONG after hospital discharge for COVID-19 (SAVE-LONG) Brief Description SAVE-LONG is a call to the development of diagnostic tools and therapeutic modalities for patients with Long-COVID Syndrome. Details Status: ongoing Study Type: Non-interventional Study phase: II &