Completed study Official Study Title suPAR-guided Anakinra treatment for Validation of the risk and Early management of severe respiratory failure by COVID-19: the SAVE open-label, non-randomized single-arm trial Brief Description SAVE is an open non-randomized clinical trial aiming to study the early treatment of patients with COVID-19 pneumonia with anakinra guided by the biomarker
Completed study Official Study Title Efficiency in management of organ dysfunction associated with infection by the novel SARS-Cov-2 virus through A PErsonalized immunotherapy approach Brief Description ESCAPE is an open non-randomized clinical trial aiming to the personalized therapy of patients with COVID-19. Using biomarkers, enrolled patients are receiving treatment with intravenous anakinra or intravenous
Aspasia Liassidou, Georgios Renieris, Dionysia-Irene Droggiti, Theologia Gkavogianni, Christakis Liassides, Labros Sabracos, Evangelos J. Giamarellos-Bourboulis, Charalampos S Siristatidis American Journal of Reproductive Immunology 2020 Mar;83(3):e13216 DOI 10.1111/aji.13216 View article 🡇 Keywords: dectin-2; infection; lipopolysaccharide; miscarriage; preterm delivery
Stelios F Assimakopoulos, Karolina Akinosoglou, Anne-Lise de Lastic, Aikaterini Skintzi, Athanasia Mouzaki, Charalambos A Gogos The American Journal of the Medical Sciences 2020 Feb;359(2):100-107 DOI: 10.1016/j.amjms.2019.10.006View article 🡇 Funding The study was funded in part by the Hellenic Institute for the Study of Sepsis (98 / 9-07-2018). Keywords: Bacteremia; Endotoxemia; Gut
Stavros Goumenos, Olga Savvidou, George Renieris, Theologia Gkavogianni, Panayiotis J Papagelopoulos, Evangelos J. Giamarellos-Bourboulis Scientific Reports 2020 Jan 28;10(1):1345 DOI 10.1038/s41598-020-58420-w View article 🡇 FundingE.J. Giamarellos-Bourboulis has received honoraria (paid to the University of Athens) from AbbVie USA, Abbott CH, Biotest Germany, Brahms GmbH, InflaRx GmbH, MSD Greece and XBiotech Inc. He has
Evdoxia Kyriazopoulou, Dimitrios Sinapidis, Stamatios Halvatzis, Dimitrios Velissaris, Nikolaos Alexiou, Vasilios Kosmas, Maria-Evangelia Adami, Miltiades Kyprianou, Aikaterini Kyprianou, Aggelos Stefos, Malvina Lada, Pantelis Koutoukas, Maria Pavlaki, Anna Kyriakoudi, Anna Makina, Charalambos Gogos, Michael S Niederman, Evangelos J. Giamarellos-Bourboulis International Journal of Antimicrobial Agents 2020 Jan;55(1):105836 DOI: 10.1016/j.ijantimicag.2019.10.017View article 🡇 Funding The works were
Christos Nodaras, Antigoni Kotsaki, Nikolaos Tziolos, Theano Kontopoulou, Karolina Akinosoglou, Maria Chrisanthakopoulou, Eleftheria Kranidioti, Ioannis Kritselis, Nikolaos Voloudakis, Vassilios Vittoros, Agathoniki Gogkou, Ilias Fillas, Konstantinos G Toutouzas, Magdalini Bristianou, Dimosthenis Tsoutsos, Eirini Christaki, George Adamis, Katerina Kaziani, Christos Tsironis, Malvina Lada, Evangelos Kokkinakis, Styliani Sympardi, Ioannis M Koutelidakis, Achilleas Karkamanis, Aikaterini Pantazi, Cihat Bayram,
Eleni Karakike, Evdoxia Kyriazopoulou, Iraklis Tsangaris, Christina Routsi, Jean-Louis Vincent, Evangelos J. Giamarellos-Bourboulis Critical Care 2019 Nov 29;23(1):387 DOI: 10.1186/s13054-019-2665-5Download pdf 🡇 Funding The study was funded by unrestricted educational grants provided by the Hellenic Institute for the Study of Sepsis and, by the Horizon 2020 Marie Skłodowska-Curie Grant European Sepsis Academy (grant
Ongoing study Official Study Title Gut-derived INCREtin hormones in the pathophysiology of Type 1 DiaBetes MeLlitus; Effect of Metformin treatment (the INCREDIBLE-ME trial) Brief Description INCREDIBLE-ME is a randomized clinical trial aiming to study the effect of adjunct metformin treatment to insulin monotherapy in patients with type 1 diabetes, targeting the intestinal incretin secretion.
Completed study Official Study Title Pulse PhotoplethysmogAaphy as an early tool for the diagnosis of sepsis thrOUgh a two-stage Development approach Brief Description PROUD-1 is an interventional trial aiming to validate the diagnostic accuracy of a new optical biosensor for the diagnosis of sepsis and for COVID-19. Details Status: Completed Study Type: Interventional