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17October, 2018
MicroRNAs 143 and 150 in whole blood enable detection of T-cell immunoparalysis in sepsis

Categories: Biomarkers, Publications|Tags: , |

Patrick Möhnle, Simon Hirschberger, Ludwig Christian Giuseppe Hinske, Josef Briegel, Max Hübner, Sebastien Weis, Georgios Dimopoulos, Michael Bauer, Evangelos J. Giamarellos-Bourboulis, Simone Kreth Molecular Medicine 2018 Oct 17;24(1):54 DOI: 10.1186/s10020-018-0056-zDownload pdf 🡇 Funding This work has been funded by the Charles-Evans-Foundation, New Jersey, USA. Sebastian Weis and Michael

1October, 2018
Early increase of VEGF-A is associated with resolution of ventilator-associated pneumonia: Clinical and experimental evidence

Categories: Other Grants, Publications|Tags: , |

Ioannis Strouvalis, Christina Routsi, Maria Adamopoulou, Maria Raftogiannis, George Renieris, Stylianos E Orfanos, Anastasia Kotanidou, Labros Sabracos, Evangelos J. Giamarellos-Bourboulis Respirology 2018 Oct;23(10):942-949 DOI: 10.1111/resp.13320View article 🡇 Funding The study was funded by the Hellenic Institute for the Study of Sepsis. Keywords: Pseudomonas; outcome; pneumonia; vascular endothelial

1October, 2018
How well does qSOFA correspond to underlying systemic inflammatory response?

Categories: Biomarkers, Publications|Tags: , |

Karolina Akinosoglou, Spyridoula Theodoraki, Theologia Gkavogianni, Aikaterini Pistiki, Evangelos J. Giamarellos-Bourboulis, Charalambos A Gogos Cytokine 2018 Oct;110:288-290 DOI: 10.1016/j.cyto.2018.01.019View article 🡇 Funding The study was funded by the Hellenic Institute for the Study of Sepsis. Keywords: Anti-inflammatory mediators; Pro-inflammatory mediators; SIRS; Sepsis; qSOFA

1August, 2018
Complement activation in hidradenitis suppurativa: a new pathway of pathogenesis?

Categories: Publications|Tags: |

Theodora Kanni, Othmar Zenker, Maria Habel, Niels C Riedemann, Evangelos J. Giamarellos-Bourboulis British Journal of Dermatology 2018 Aug;179(2):413-419 DOI: 10.1111/bjd.16428View article 🡇 Funding This study was funded in part by InflaRx GmbH, Jena, Germany, and in part by the Hellenic Institute for the Study of Sepsis. Keywords:

1June, 2018
Reduced circulating B cells and plasma IgM levels are associated with decreased survival in sepsis – A meta-analysis

Categories: Biomarkers, Publications|Tags: , |

Christian Krautz, Sarah L Maier, Maximilian Brunner, Melanie Langheinrich, Evangelos J. Giamarellos-Bourboulis, Charalambos Gogos, Apostolos Armaganidis, Frank Kunath, Robert Grützmann, Georg F Weber Journal of Critical Care 2018 Jun;45:71-75 DOI: 10.1016/j.jcrc.2018.01.013 View article 🡇 Keywords: Circulating B cells; Plasma IgM; Sepsis; Sepsis outcome

29May, 2018
Progression into sepsis: an individualized process varying by the interaction of comorbidities with the underlying infection

Categories: Pathogenesis, Publications|Tags: |

Dimitrios Sinapidis, Vassileios Kosmas, Vasileios Vittoros, Ioannis M. Koutelidakis, Aikaterini Pantazi, Aggelos Stefos, Konstantinos E. Katsaros, Karolina Akinosoglou, Magdalini Bristianou, Konstantinos Toutouzas, Michael Chrisofos and Evangelos J. Giamarellos-Bourboulis BMC Infectious Diseases, May 2018 DOI 10.1186/s12879-018-3156-zDownload pdf 🡇 Funding The study was funded by the Hellenic Institute for

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