Sepsis

1 January, 2021

Diabetes on sepsis outcomes in non-ICU patients: A cohort study and review of the literature

2023-02-16T13:36:16+03:00By hiss|Categories: Biomarkers, Publications|Tags: diabetes, Sepsis|

Karolina Akinosoglou, Georgia Kapsokosta, Maria Mouktaroudi, Nikoletta Rovina, Vassileios Kaldis, Aggelos Stefos, Marina Kontogiorgi, Evangelos J. Giamarellos-Bourboulis, Charalambos Gogos, Hellenic Sepsis Study Group Journal of Diabetes and Its Complications 2021 Jan;35(1):107765 DOI: 10.1016/j.jdiacomp.2020.107765View article 🡇 Funding The works were supported by the BMBF within the framework of the “MetaZIK”/ZIK Septomics Jena (03Z2J521),

1 December, 2020

De-escalation of antimicrobial therapy in ICU settings with high prevalence of multidrug-resistant bacteria: a multicentre prospective observational cohort study in patients with sepsis or septic shock

2023-02-16T13:36:45+03:00By hiss|Categories: Multicenter studies in Greece, Publications|Tags: Sepsis, SOFA|

Christina Routsi, Aikaterini Gkoufa, Kostoula Arvaniti, Stelios Kokkoris, Alexandros Tourtoglou, Vassiliki Theodorou, Anna Vemvetsou, Georgios Kassianidis, Athena Amerikanou, Elisabeth Paramythiotou, Efstathia Potamianou, Kyriakos Ntorlis, Angeliki Kanavou, Georgios Nakos, Eleftheria Hassou, Helen Antoniadou, Ilias Karaiskos, Athanasios Prekates, Apostolos Armaganidis, Ioannis Pnevmatikos, Miltiades Kyprianou, Spyros Zakynthinos, Garyfallia Poulakou, Helen Giamarellou Journal of Antimicrobial Chemotherapy 2020 Dec

19 November, 2020

A novel optical biosensor for the early diagnosis of sepsis and severe Covid-19: the PROUD study

2024-03-29T13:55:21+03:00By hiss|Categories: Biomarkers, Publications|Tags: clinical trial, COVID-19, Sepsis|

Sarantia Doulou, Konstantinos Leventogiannis, Maria Tsilika, Matthew Rodencal, Konstantina Katrini, Nikolaos Antonakos, Miltiades Kyprianou, Emmanouil Karofylakis, Athanassios Karageorgos, Panagiotis Koufargyris, Gennaios Christopoulos, George Kassianidis, Kimon Stamatelopoulos, Robert Newberry, Evangelos J. Giamarellos-Bourboulis BMC Infectious Diseases 2020 Nov 19;20(1):860 DOI: 10.1186/s12879-020-05607-1Download pdf 🡇 Funding The study was funded in part by the Hellenic Institute

2 February, 2020

The Prognostic Value of Endotoxemia and Intestinal Barrier Biomarker ZO-1 in Bacteremic Sepsis

2023-02-16T14:30:16+03:00By hiss|Categories: Other Grants, Pathogenesis, Publications|Tags: Sepsis|

Stelios F Assimakopoulos, Karolina Akinosoglou, Anne-Lise de Lastic, Aikaterini Skintzi, Athanasia Mouzaki, Charalambos A Gogos The American Journal of the Medical Sciences 2020 Feb;359(2):100-107 DOI: 10.1016/j.amjms.2019.10.006View article 🡇 Funding The study was funded in part by the Hellenic Institute for the Study of Sepsis (98 / 9-07-2018). Keywords: Bacteremia; Endotoxemia; Gut

29 November, 2019

The early change of SOFA score as a prognostic marker of 28-day sepsis mortality: analysis through a derivation and a validation cohort

2024-03-29T13:19:02+03:00By hiss|Categories: Biomarkers, Publications|Tags: Sepsis, SOFA|

Eleni Karakike, Evdoxia Kyriazopoulou, Iraklis Tsangaris, Christina Routsi, Jean-Louis Vincent, Evangelos J. Giamarellos-Bourboulis Critical Care 2019 Nov 29;23(1):387 DOI: 10.1186/s13054-019-2665-5Download pdf 🡇 Funding The study was funded by unrestricted educational grants provided by the Hellenic Institute for the Study of Sepsis and, by the Horizon 2020 Marie Skłodowska-Curie Grant European Sepsis Academy (grant

1 November, 2019

PROUD-1

2023-01-09T12:14:18+03:00By hiss|Categories: Completed, Interventional, Sepsis and severe infections, Studies|Tags: COVID-19, Sepsis|

Completed study Official Study Title Pulse PhotoplethysmogAaphy as an early tool for the diagnosis of sepsis thrOUgh a two-stage Development approach Brief Description PROUD-1 is an interventional trial aiming to validate the diagnostic accuracy of a new optical biosensor for the diagnosis of sepsis and for COVID-19. Details Status: Completed Study Type: Interventional

1 September, 2019

Late Peaks of HMGB1 and Sepsis Outcome: Evidence For Synergy With Chronic Inflammatory Disorders

2023-02-16T14:34:19+03:00By hiss|Categories: Publications|Tags: diabetes, Sepsis|

Eleni Karakike, Maria-Evangelia Adami, Malvina Lada, Theologia Gkavogianni, Ioannis M Koutelidakis, Michael Bauer, Evangelos J. Giamarellos-Bourboulis, Iraklis Tsangaris Shock 2019 Sep;52(3):334-339 DOI 10.1097/SHK.0000000000001265 View article 🡇 Funding The study was funded by unrestricted educational grants provided by the Hellenic Institute for the Study of Sepsis, by the Horizon 2020 Marie

1 June, 2019

Association of the early absolute CD64-expressing neutrophil count and sepsis outcome

2023-02-16T14:34:38+03:00By hiss|Categories: Biomarkers, Other Grants, Publications|Tags: metabolism, Sepsis, SOFA|

Aggeliki Xini, Aikaterini Pistiki, Malvina Lada, Evangelos J. Giamarellos-Bourboulis, Georgios Dimopoulos European Journal of Clinical Microbiology & Infectious Diseases 2019 Jun;38(6):1123-1128 DOI: 10.1007/s10096-019-03507-0View article 🡇 FundingThe study was funded by the Hellenic Institute for the Study of Sepsis. The funders did not have any role in the study design, analysis, and interpretation of data

31 January, 2019

Macrophage Activation-Like Syndrome: A Distinct Entity Leading to Early Death in Sepsis.

2023-02-16T14:36:48+03:00By hiss|Categories: Publications|Tags: Sepsis|

Eleni Karakike , Evangelos J. Giamarellos-Bourboulis Frontiers in Immunology 2019 Jan 31;10:55 DOI 10.3389/fimmu.2019.00055 View article 🡇 Funding EK is funded by the Horizon 2020 Marie Skłodowska-Curie Grant European Sepsis Academy (grant 676129 paid to the University of Athens). EG-B has received funding from the FrameWork 7 program HemoSpec and

17 October, 2018

MicroRNAs 143 and 150 in whole blood enable detection of T-cell immunoparalysis in sepsis

2024-03-28T18:19:40+03:00By hiss|Categories: Biomarkers, Publications|Tags: miRNA, Sepsis|

Patrick Möhnle, Simon Hirschberger, Ludwig Christian Giuseppe Hinske, Josef Briegel, Max Hübner, Sebastien Weis, Georgios Dimopoulos, Michael Bauer, Evangelos J. Giamarellos-Bourboulis, Simone Kreth Molecular Medicine 2018 Oct 17;24(1):54 DOI: 10.1186/s10020-018-0056-zDownload pdf 🡇 Funding This work has been funded by the Charles-Evans-Foundation, New Jersey, USA. Sebastian Weis and Michael Bauer are supported by the