1 October, 2017

INTELLIGENCE-1

2023-01-09T12:10:28+03:00By |Categories: Completed, Non-Interventional, Sepsis and severe infections, Studies|Tags: |

Completed study Official Study Title INTEgration of clinicaL and Laboratory Information to GENerate technological advanCE for the diagnosis of sepsis Brief Description INTELLIGENCE-1 is a non-interventional trial to validate the diagnostic accuracy of HemoSpec in the diagnosis of sepsis. HemoSpec is a device that integrates information of whole blood cell count, Raman spectra of

1 October, 2017

PROGRESS

2023-01-09T12:14:39+03:00By |Categories: Completed, Interventional, Sepsis and severe infections, Studies|Tags: , |

Completed study Official Study Title A randomized prospective clinical trial to assess the role of PROcalcitonin-Guided antimicrobial therapy to REduce long-term infectionS Sequelae Brief Description PROGRESS is a randomized clinical trial aiming to test the efficacy of an algorithm of the duration of antimicrobial treatment based on serum procalcitonin in patients with sepsis on

1 October, 2017

Increase of circulating endocan over sepsis follow-up is associated with progression into organ dysfunction

2023-02-16T15:11:50+03:00By |Categories: Biomarkers, Publications|Tags: |

Aikaterini Ioakeimidou, E Pagalou, Marina Kontogiorgi, Eleni Antoniadou, Katerina Kaziani, Konstantinos Psaroulis, Evangelos J. Giamarellos-Bourboulis, Athanasios Prekates, Nikolaos Antonakos, P Lassale, Charalambos Gogos; Hellenic Sepsis Study Group European Journal of Clinical Microbiology & Infectious Diseases 2017 Oct;36(10):1749-1756 DOI: 10.1007/s10096-017-2988-6View article 🡇 Funding The study was funded by the Hellenic Institute for the Study

18 September, 2017

Macrophage activation-like syndrome: an immunological entity associated with rapid progression to death in sepsis

2024-03-28T16:56:33+03:00By |Categories: Pathogenesis, Publications|Tags: |

Evdoxia Kyriazopoulou, Konstantinos Leventogiannis, Anna Norrby-Teglund, Georgios Dimopoulos, Aikaterini Pantazi, Stylianos E. Orfanos, Nikoletta Rovina, Iraklis Tsangaris, Theologia Gkavogianni, Elektra Botsa, Eleftheria Chassiou, Anastasia Kotanidou, Christina Kontouli, Panagiotis Chaloulis, Dimitrios Velissaris, Athina Savva, Jonas-Sundén Cullberg, Karolina Akinosoglou, Charalambos Gogos, Apostolos Armaganidis, Evangelos J. Giamarellos-Bourboulis on behalf of the Hellenic Sepsis Study Group BMC

1 September, 2017

PROMPT

2023-01-09T12:10:01+03:00By |Categories: Completed, Non-Interventional, Sepsis and severe infections, Studies|Tags: |

Completed study Official Study Title Prospective Multi-centre Clinical Study to Assess the Clinical Validity of the Heparin Binding Protein Assay to Indicate the Presence and Outcome of Sepsis in Patients With Suspected Infection Following Emergency Department Admission Brief Description PROMPT is a non-interventional trial aiming to validate the diagnostic accuracy of Heparin Binding Protein

9 March, 2017

Decreased cytokine production by mononuclear cells after severe gram-negative infections: early clinical signs and association with final outcome

2023-02-16T15:14:13+03:00By |Categories: Other Grants, Publications|Tags: |

Nikolaos Antonakos, Thomas Tsaganos, Volker Oberle, Iraklis Tsangaris, Malvina Lada, Aikaterini Pistiki, Nikolaos Machairas, Maria Souli, Michael Bauer, Evangelos J. Giamarellos-Bourboulis Critical Care 2017 Mar 9;21(1):48 DOI: 10.1186/s13054-017-1625-1View article 🡇 Funding The study was funded by unrestricted educational grants provided by the Hellenic Institute for the Study of Sepsis and by the

1 February, 2017

Survival after multiple traumas is associated with improved outcomes from gram-negative sepsis: Clinical and experimental evidence

2023-02-16T15:16:38+03:00By |Categories: Pathogenesis, Publications|Tags: |

Eleftherios Mandragos, Aikaterini Pistiki, Iraklis Tsangaris, Christina Routsi, Michael Paraschos, Dionyssia-Irene Droggiti, Olga Savvidou, Dimitrios Mastrokalos, Panayiotis J Papagelopoulos, Mihai G Netea, Evangelos J Giamarellos-Bourboulis Journal of Infection 2017 Feb;74(2):163-171 DOI: 10.1016/j.jinf.2016.10.007View the article 🡇 Funding The study was funded by the Hellenic Institute for the Study of Sepsis. Keywords: Cytokines; Interleukin-10; Multiple

1 February, 2017

Validation of the new Sepsis-3 definitions: proposal for improvement in early risk identification

2024-03-28T16:25:20+03:00By |Categories: Epidemiology, Publications|Tags: |

E.J. Giamarellos-Bourboulis, T. Tsaganos, I. Tsangaris, M. Lada, C. Routsi, D. Sinapidis, M. Koupetori, M. Bristianou, G. Adamis, K. Mandragos, G.N. Dalekos, I. Kritselis, G. Giannikopoulos, I. Koutelidakis, M. Pavlaki, E. Antoniadou, G. Vlachogiannis, V. Koulouras, A. Prekates, G. Dimopoulos, A. Koutsoukou, I. Pnevmatikos, A. Ioakeimidou, A. Kotanidou, S.E. Orfanos, A. Armaganidis, C. Gogos,

1 November, 2016

Change of annexin binding of monocytes as an expression of cellular response to Candida albicans: down-regulation in severe sepsis

2023-02-16T15:17:58+03:00By |Categories: Other Grants, Publications|Tags: , , |

Aikaterini Pistiki, Thomas Tsaganos, Iraklis Tsangaris, Nikolaos Antonakos, Georgia Damoraki, Evangelos J. Giamarellos-Bourboulis European Journal of Clinical Microbiology and Infectious Diseases 2016 Nov;35(11):1787-1793 DOI: 10.1007/s10096-016-2728-3View article 🡇 Funding The study was funded by the Hellenic Institute for the Study of Sepsis. Keywords: Sepsis; immunology

1 November, 2016

Soluble urokinase plasminogen activator receptor informs on the progression course after multiple injuries

2023-02-16T15:18:46+03:00By |Categories: Publications|Tags: , |

Maria Patrani, Thomas Tsaganos, Katerina Kotzampassi, Michael Paraschos, Chrysostomos Katsenos, Evangelos J. Giamarellos-Bourboulis, Konstantinos Mandragos Biomarkers 2016 Nov;21(7):660-4 DOI 10.1016/j.cyto.2022.15611 View article 🡇 Funding The study was funded in part by (a) the Hellenic Institute for the Study of Sepsis; and (b) an unrestricted educational grant by ViroGates SA, Copenhagen,

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