Rainer König, Amol Kolte, Olaf Ahlers, Marcus Oswald, Veiko Krauss, Daniela Roell, Oliver Sommerfeld, George Dimopoulos, Iraklis Tsangaris, Eleni Antoniadou, Neeraja Jaishankar, Holger Bogatsch, Markus Löffler, Markus Rödel, Marina Garcia-Moreno, Lorena Tuchscherr, Charles L Sprung, Mervyn Singer, Frank Brunkhorst, Michael Oppert, Herwig Gerlach, Ralf A Claus, Sina M Coldewey, Josef Briegel, Evangelos J. Giamarellos-Bourboulis, Didier Keh, Michael Bauer
Frontiers in Immunology 2021 Mar 9;12:607217
DOI 10.3389/fimmu.2021.607217
Funding
This work has been supported by the Federal Ministry of Education and Research (BMBF), Germany, FKZ: 01EO1002, 01EO1502 (CSCC), and FKZ 01ZX1302B, 01ZX1602B (CancerTel-Sys), 03Z22JN12 (Translational Septomics), 13N13890 (Inter-Sept), the Deutsche Forschungsgemeinschaft (DFG) (KO 3678/5-1) and department funds of the Department of Anesthesiology and Intensive Care Medicine, Jena University Hospital. The CORTICUS immune substudy (Berlin substudy) was supported by the German Research Foundation (Deutsche Forschungsgemeinschaft, DFG): KE 870 1-1 and 1-2, and by department funds of the Department of Anesthesiology and Operative Intensive Care Medicine (CCM, CVK), Charité – Universitätsmedizin Berlin.
Keywords: IFNgamma/IL10; hydrocortisone; immune therapy; machine learning; sepsis; steroids; theranostics