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So far hiss has created 170 blog entries.
31 July, 2019

HALO

2023-01-16T02:18:39+03:00By |Categories: Completed, Sepsis and severe infections, Studies|

Completed study Official Study Title Heparin AnticoaguLation to improve Outcomes in septic shock: The HALO international phase II RCT Brief Description HALO-HCA2017 is a randomized clinical trial aiming to study if heparin, a widely available, inexpensive anticoagulant, may improve clinical outcomes in patients with septic shock. Details Status: Completed Study Type: Interventional (Clinical

1 July, 2019

LIGHT

2023-01-09T12:07:43+03:00By |Categories: Completed, Interventional, Studies, Systemic inflammatory disorders|Tags: |

Completed study Official Study Title A double-blind, randomised, placebo-controlled clinical trial of the safety and efficacy of MABp1, a- first-in-class true human antibody targeting interleukin-1alpha, in patients with hidradenitis suppurativa not eligible for adalimumab Brief Description LIGHT is a double-blind randomized study aiming to the comparison of the efficacy of MABp1 (Bermekimab), a fully

1 June, 2019

Association of the early absolute CD64-expressing neutrophil count and sepsis outcome

2023-02-16T14:34:38+03:00By |Categories: Biomarkers, Other Grants, Publications|Tags: , , |

Aggeliki Xini, Aikaterini Pistiki, Malvina Lada, Evangelos J. Giamarellos-Bourboulis, Georgios Dimopoulos European Journal of Clinical Microbiology & Infectious Diseases 2019 Jun;38(6):1123-1128 DOI: 10.1007/s10096-019-03507-0View article 🡇 FundingThe study was funded by the Hellenic Institute for the Study of Sepsis. The funders did not have any role in the study design, analysis, and interpretation of data

1 June, 2019

Association between genotypes of rs34436714 of NLRP12 and serum tumor necrosis factor-alpha in inflammatory bowel disease: A case-control study

2023-02-16T14:34:56+03:00By |Categories: Publications|Tags: |

Erminia Dellaporta, Lazaros-Dimitrios Lazaridis, Vasilleios Koussoulas, Mihai G Netea, Evangelos J. Giamarellos-Bourboulis, Konstantinos Triantafyllou Medicine 2019 Jun;98(23):e15913 DOI 10.1097/MD.0000000000015913 View article 🡇 Funding M.G. Netea is supported by a Dutch Vici grant. E.J. Giamarellos-Bourboulis has received honoraria (paid to the University of Athens) from AbbVie, Biotest, Brahms GmbH, and The

1 May, 2019

Cost-savings of adalimumab in hidradenitis suppurativa: a retrospective analysis of a real-world cohort

2023-02-16T14:35:12+03:00By |Categories: Publications|Tags: |

Maria Argyropoulou, Theodora Kanni, Miltiades Kyprianou, Nikolaos Melachroinopoulos, Evangelos J. Giamarellos-Bourboulis British Journal of Dermatology 2019 May;180(5):1161-1168 DOI: 10.1111/bjd.17151View article 🡇 Funding The study was funded by the Hellenic Institute for the Study of Sepsis. The funder did not have any involvement in the study design, data collection, data analysis, manuscript preparation or

1 March, 2019

Early changes of the heat-shock protein 60 to 70 ratio as prediction of miscarriage in pregnancy

2023-02-16T14:35:32+03:00By |Categories: Other Grants, Publications|Tags: |

Aggeliki Makri, Charalampos Siristatidis, Charalampos Chrelias, Chrysi Christodoulaki, Nikolaos Evangelinakis, Dimitrios Kassanos, Evangelos J. Giamarellos-Bourboulis, Aikaterini Pistiki American Journal of Reproductive Immunology 2019 Mar;81(3):e13087 DOI: 10.1111/aji.13087View article 🡇 Funding Hellenic Institute for the Study of Sepsis Keywords: heat-shock protein 60; heat-shock protein 70; miscarriage

31 January, 2019

Macrophage Activation-Like Syndrome: A Distinct Entity Leading to Early Death in Sepsis.

2023-02-16T14:36:48+03:00By |Categories: Publications|Tags: |

Eleni Karakike , Evangelos J. Giamarellos-Bourboulis Frontiers in Immunology 2019 Jan 31;10:55 DOI 10.3389/fimmu.2019.00055 View article 🡇 Funding EK is funded by the Horizon 2020 Marie Skłodowska-Curie Grant European Sepsis Academy (grant 676129 paid to the University of Athens). EG-B has received funding from the FrameWork 7 program HemoSpec and

2 January, 2019

Daptomycin as adjunctive treatment for experimental infection by Acinetobacter baumannii with resistance to colistin

2023-02-16T14:36:43+03:00By |Categories: Other Grants, Publications|Tags: |

Garyfallia Poulakou, Georgios Renieris, Labros Sabrakos, Olympia Zarkotou, Katherine Themeli-Digalaki, Efstathia Perivolioti, Eleni Kraniotaki,  Evangelos J. Giamarellos-Bourboulis, Nikolaos Zavras International Journal of Antimicrobial Agents 2019 Feb;53(2):190-194 DOI: 10.1016/j.ijantimicag.2018.10.024View article 🡇 Funding This study was funded by the Hellenic Institute for the Study of Sepsis. The funding source was not involved in the study

17 October, 2018

MicroRNAs 143 and 150 in whole blood enable detection of T-cell immunoparalysis in sepsis

2024-03-28T18:19:40+03:00By |Categories: Biomarkers, Publications|Tags: , |

Patrick Möhnle, Simon Hirschberger, Ludwig Christian Giuseppe Hinske, Josef Briegel, Max Hübner, Sebastien Weis, Georgios Dimopoulos, Michael Bauer, Evangelos J. Giamarellos-Bourboulis, Simone Kreth Molecular Medicine 2018 Oct 17;24(1):54 DOI: 10.1186/s10020-018-0056-zDownload pdf 🡇 Funding This work has been funded by the Charles-Evans-Foundation, New Jersey, USA. Sebastian Weis and Michael Bauer are supported by the

1 October, 2018

Early increase of VEGF-A is associated with resolution of ventilator-associated pneumonia: Clinical and experimental evidence

2023-02-16T14:37:42+03:00By |Categories: Other Grants, Publications|Tags: , |

Ioannis Strouvalis, Christina Routsi, Maria Adamopoulou, Maria Raftogiannis, George Renieris, Stylianos E Orfanos, Anastasia Kotanidou, Labros Sabracos, Evangelos J. Giamarellos-Bourboulis Respirology 2018 Oct;23(10):942-949 DOI: 10.1111/resp.13320View article 🡇 Funding The study was funded by the Hellenic Institute for the Study of Sepsis. Keywords: Pseudomonas; outcome; pneumonia; vascular endothelial growth factor

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