Completed study Official Study Title a SUPar guided doublE-blind Randomized clinical trial of Initiation Of antibiotics foR presumed infection at the emergency department Brief Description SUPERIOR is a randomized clinical trial aiming to evaluate suPAR - guided medical intervention, consisting of early antibiotic administration at the emergency room for presumed infection and sepsis and
Karolina Akinosoglou, Spyridoula Theodoraki, Theologia Gkavogianni, Aikaterini Pistiki, Evangelos J. Giamarellos-Bourboulis, Charalambos A Gogos Cytokine 2018 Oct;110:288-290 DOI: 10.1016/j.cyto.2018.01.019View article 🡇 Funding The study was funded by the Hellenic Institute for the Study of Sepsis. Keywords: Anti-inflammatory mediators; Pro-inflammatory mediators; SIRS; Sepsis; qSOFA
Theodora Kanni, Othmar Zenker, Maria Habel, Niels C Riedemann, Evangelos J. Giamarellos-Bourboulis British Journal of Dermatology 2018 Aug;179(2):413-419 DOI: 10.1111/bjd.16428View article 🡇 Funding This study was funded in part by InflaRx GmbH, Jena, Germany, and in part by the Hellenic Institute for the Study of Sepsis. Keywords: Hidradenitis Suppurativa; immunology; biomarkers
Christian Krautz, Sarah L Maier, Maximilian Brunner, Melanie Langheinrich, Evangelos J. Giamarellos-Bourboulis, Charalambos Gogos, Apostolos Armaganidis, Frank Kunath, Robert Grützmann, Georg F Weber Journal of Critical Care 2018 Jun;45:71-75 DOI: 10.1016/j.jcrc.2018.01.013 View article 🡇 Keywords: Circulating B cells; Plasma IgM; Sepsis; Sepsis outcome
Dimitrios Sinapidis, Vassileios Kosmas, Vasileios Vittoros, Ioannis M. Koutelidakis, Aikaterini Pantazi, Aggelos Stefos, Konstantinos E. Katsaros, Karolina Akinosoglou, Magdalini Bristianou, Konstantinos Toutouzas, Michael Chrisofos and Evangelos J. Giamarellos-Bourboulis BMC Infectious Diseases, May 2018 DOI 10.1186/s12879-018-3156-zDownload pdf 🡇 Funding The study was funded by the Hellenic Institute for the Study of Sepsis.
Theodora Kanni, Maria Argyropoulou, Themistoklis Spyridopoulos, Aikaterini Pistiki, Michael Stecher, Charles A Dinarello, John Simard, Evangelos J. Giamarellos-Bourboulis Journal of Investigative Dermatology 2018 Apr;138(4):795-801 DOI: 10.1016/j.jid.2017.10.030View article 🡇 Funding This study was supported in part by XBiotech (Austin, TX) and the Hellenic Institute for the Study of Sepsis. Keywords: Hidradenitis Suppurativa Related
Gabriela Gainaru, Antonios Papadopoulos, Iraklis Tsangaris, Malvina Lada, Evangelos J. Giamarellos-Bourboulis, Aikaterini Pistiki Critical Care 2018 Mar 3;22(1):56 DOI: 10.1186/s13054-018-1977-1View article 🡇 Funding The study was funded by the Hellenic Institute for the Study of Sepsis. Keywords: Gram-negative; Inflammatory monocytes; Patrolling monocytes; Sepsis; Survival
Theodoros Retsas, Klaus Huse, Lazaros-Dimitrios Lazaridis, Niki Karampela, Michael Bauer, Matthias Platzer, Virginia Kolonia, Eirini Papageorgiou, Evangelos J. Giamarellos-Bourboulis, George Dimopoulos International Journal of Infectious Diseases 2018 Feb;67:102-106 DOI: 10.1016/j.ijid.2017.12.008Download pdf 🡇 FundingThe study was funded in part by the Hellenic Institute for the Study of Sepsis and by the Federal Ministry of
Completed study Official Study Title A Personalized Randomized Trial of Validation and Restoration of Immune Dysfunction in Severe Infections and Sepsis (PROVIDE) Brief Description PROVIDE is a randomized clinical trial aiming to the personalized therapy of patients at septic shock. Using biomarkers, enrolled patients are randomized through a double-dummy approach to immunotherapy or placebo
Completed study Official Study Title A randomized Clinical Trial for enhanced trained Immune responses through bacillus calmette-guérin VAccination to prevenT infections of the Elderly (ACTIVATE) Brief Description ACTIVATE is a randomized clinical trial aiming to investigate if the developing concept of trained immunity i.e. the memory of the innate immune system coming after vaccination