hiss, Author at HISS

29 November, 2019

The early change of SOFA score as a prognostic marker of 28-day sepsis mortality: analysis through a derivation and a validation cohort

2024-03-29T13:19:02+03:00By hiss|Categories: Biomarkers, Publications|Tags: Sepsis, SOFA|

Eleni Karakike, Evdoxia Kyriazopoulou, Iraklis Tsangaris, Christina Routsi, Jean-Louis Vincent, Evangelos J. Giamarellos-Bourboulis Critical Care 2019 Nov 29;23(1):387 DOI: 10.1186/s13054-019-2665-5Download pdf 🡇 Funding The study was funded by unrestricted educational grants provided by the Hellenic Institute for the Study of Sepsis and, by the Horizon 2020 Marie Skłodowska-Curie Grant European Sepsis Academy (grant

1 November, 2019

INCREDIBLE-ME

2023-01-09T12:12:10+03:00By hiss|Categories: Interventional, Ongoing, Sepsis and severe infections, Studies|Tags: diabetes|

Ongoing study Official Study Title Gut-derived INCREtin hormones in the pathophysiology of Type 1 DiaBetes MeLlitus; Effect of Metformin treatment (the INCREDIBLE-ME trial) Brief Description INCREDIBLE-ME is a randomized clinical trial aiming to study the effect of adjunct metformin treatment to insulin monotherapy in patients with type 1 diabetes, targeting the intestinal incretin secretion.

1 November, 2019

PROUD-1

2023-01-09T12:14:18+03:00By hiss|Categories: Completed, Interventional, Sepsis and severe infections, Studies|Tags: COVID-19, Sepsis|

Completed study Official Study Title Pulse PhotoplethysmogAaphy as an early tool for the diagnosis of sepsis thrOUgh a two-stage Development approach Brief Description PROUD-1 is an interventional trial aiming to validate the diagnostic accuracy of a new optical biosensor for the diagnosis of sepsis and for COVID-19. Details Status: Completed Study Type: Interventional

7 October, 2019

Past history of stage I/II solid tumor malignancy impacts considerably on sepsis mortality: a propensity score matching analysis from the hellenic sepsis study group

2023-02-16T14:33:02+03:00By hiss|Categories: Publications|Tags: cancer, ICU|

George Dimopoulos, Nikoletta Rovina, Maria Patrani, Eleni Antoniadou, Dimitrios Konstantonis, Konstantina Vryza, Glykeria Vlachogianni, Miltiades Kyprianou, Christina Routsi, Evangelos J. Giamarellos-Bourboulis; Hellenic Sepsis Study Group BMC Infectious Diseases 2019 Oct 7;19(1):831 DOI 10.1186/s12879-019-4448-7 View article 🡇 Funding The study was funded by the Hellenic Institute for the Study of Sepsis.

1 October, 2019

Susceptibility profiles and clinical efficacy of antifungals against candida bloodstream isolates from critically ill patients: Focus on intravenous itraconazole

2023-02-16T14:33:27+03:00By hiss|Categories: Publications, Therapeutics|Tags: Candida, Itraconazole|

Evangelos J. Giamarellos-Bourboulis, Aliki Stamou, Sofia Maraki, Nicky Solomonidi, Eleni Belesiotou, Aikaterini Pistiki, Eleni Antoniadou, Glykeria Vlachogianni, Konstantinos Mandragos, Chronis Tasioudis, Chrisostomos Katsenos, Christina Routsi, George Samonis, George Dimopoulos International Journal of Antimicrobial Agents 2019 Oct;54(4):471-477 DOI: 10.1016/j.ijantimicag.2019.06.019View article 🡇 Funding The study was funded by the Hellenic Institute for the Study of

1 October, 2019

Single nucleotide polymorphisms of Toll-like receptor-4 and of autophagy-related gene 16 like-1 gene for predisposition of premature delivery: A prospective study

2023-02-16T14:33:47+03:00By hiss|Categories: Publications|Tags: PhD|

Christakis Liassides, Antonios Papadopoulos, Charalampos Siristatidis, Georgia Damoraki, Aspasia Liassidou, Charalampos Chrelias, Dimitrios Kassanos, Evangelos J. Giamarellos-Bourboulis Medicine 2019 Oct;98(40):e17313 DOI 10.1097/MD.0000000000017313 View article 🡇 Funding This study was funded by the Hellenic Institute for the Study of Sepsis. Keywords: autophagy; preterm delivery; single nucleotide polymorphisms; toll-like receptor-4

1 September, 2019

Late Peaks of HMGB1 and Sepsis Outcome: Evidence For Synergy With Chronic Inflammatory Disorders

2023-02-16T14:34:19+03:00By hiss|Categories: Publications|Tags: diabetes, Sepsis|

Eleni Karakike, Maria-Evangelia Adami, Malvina Lada, Theologia Gkavogianni, Ioannis M Koutelidakis, Michael Bauer, Evangelos J. Giamarellos-Bourboulis, Iraklis Tsangaris Shock 2019 Sep;52(3):334-339 DOI 10.1097/SHK.0000000000001265 View article 🡇 Funding The study was funded by unrestricted educational grants provided by the Hellenic Institute for the Study of Sepsis, by the Horizon 2020 Marie

31 July, 2019

HALO

2023-01-16T02:18:39+03:00By hiss|Categories: Completed, Sepsis and severe infections, Studies|

Completed study Official Study Title Heparin AnticoaguLation to improve Outcomes in septic shock: The HALO international phase II RCT Brief Description HALO-HCA2017 is a randomized clinical trial aiming to study if heparin, a widely available, inexpensive anticoagulant, may improve clinical outcomes in patients with septic shock. Details Status: Completed Study Type: Interventional (Clinical

1 July, 2019

LIGHT

2023-01-09T12:07:43+03:00By hiss|Categories: Completed, Interventional, Studies, Systemic inflammatory disorders|Tags: Hidradenitis suppurativa|

Completed study Official Study Title A double-blind, randomised, placebo-controlled clinical trial of the safety and efficacy of MABp1, a- first-in-class true human antibody targeting interleukin-1alpha, in patients with hidradenitis suppurativa not eligible for adalimumab Brief Description LIGHT is a double-blind randomized study aiming to the comparison of the efficacy of MABp1 (Bermekimab), a fully

1 June, 2019

Association of the early absolute CD64-expressing neutrophil count and sepsis outcome

2023-02-16T14:34:38+03:00By hiss|Categories: Biomarkers, Other Grants, Publications|Tags: metabolism, Sepsis, SOFA|

Aggeliki Xini, Aikaterini Pistiki, Malvina Lada, Evangelos J. Giamarellos-Bourboulis, Georgios Dimopoulos European Journal of Clinical Microbiology & Infectious Diseases 2019 Jun;38(6):1123-1128 DOI: 10.1007/s10096-019-03507-0View article 🡇 FundingThe study was funded by the Hellenic Institute for the Study of Sepsis. The funders did not have any role in the study design, analysis, and interpretation of data

About hiss