Completed study Official Study Title A double-blind, randomized, placebo-controlled clinical study of the efficacy of INtravenous CLArithromycin as adjunctive treatment in patients with Sepsis and respiratory and multiple organ dysfunction Syndrome Brief Description INCLASS is a randomized clinical trial aiming to compare the efficacy of intravenous clarithromycin over placebo in patients with sepsis and
Karolina Akinosoglou, Spyridoula Theodoraki, Ioanna Xanthopoulou, Angelos Perperis, Theologia Gkavogianni, Aikaterini Pistiki, Evangelos J Giamarellos-Bourboulis, Charalambos A Gogos European Journal of Clinical Microbiology & Infectious Diseases 2017 Dec;36(12):2503-2512 DOI: 10.1007/s10096-017-3093-6View the article 🡇 Funding This work was funded by the Hellenic Institute for the Study of Sepsis. Keywords: Organ dysfunction; P2Y12 platelet
S Christodoulou, E Kyriazopoulou, M Chrysanthakopoulou, G Karlis, I Karampela, K Gkizeli, N Veliki, A Safarika, E J Giamarellos-Bourboulis, G Adamis; Hellenic Sepsis Study Group European Journal of Clinical Microbiology & Infectious Diseases 2017 Nov;36(11):2171-2177 DOI: 10.1007/s10096-017-3041-5View article 🡇 Funding The study was funded by the Hellenic Institute for the Study of Sepsis.
Completed study Official Study Title INTEgration of clinicaL and Laboratory Information to GENerate technological advanCE for the diagnosis of sepsis Brief Description INTELLIGENCE-1 is a non-interventional trial to validate the diagnostic accuracy of HemoSpec in the diagnosis of sepsis. HemoSpec is a device that integrates information of whole blood cell count, Raman spectra of
Completed study Official Study Title A randomized prospective clinical trial to assess the role of PROcalcitonin-Guided antimicrobial therapy to REduce long-term infectionS Sequelae Brief Description PROGRESS is a randomized clinical trial aiming to test the efficacy of an algorithm of the duration of antimicrobial treatment based on serum procalcitonin in patients with sepsis on
Aikaterini Ioakeimidou, E Pagalou, Marina Kontogiorgi, Eleni Antoniadou, Katerina Kaziani, Konstantinos Psaroulis, Evangelos J. Giamarellos-Bourboulis, Athanasios Prekates, Nikolaos Antonakos, P Lassale, Charalambos Gogos; Hellenic Sepsis Study Group European Journal of Clinical Microbiology & Infectious Diseases 2017 Oct;36(10):1749-1756 DOI: 10.1007/s10096-017-2988-6View article 🡇 Funding The study was funded by the Hellenic Institute for the Study
Evdoxia Kyriazopoulou, Konstantinos Leventogiannis, Anna Norrby-Teglund, Georgios Dimopoulos, Aikaterini Pantazi, Stylianos E. Orfanos, Nikoletta Rovina, Iraklis Tsangaris, Theologia Gkavogianni, Elektra Botsa, Eleftheria Chassiou, Anastasia Kotanidou, Christina Kontouli, Panagiotis Chaloulis, Dimitrios Velissaris, Athina Savva, Jonas-Sundén Cullberg, Karolina Akinosoglou, Charalambos Gogos, Apostolos Armaganidis, Evangelos J. Giamarellos-Bourboulis on behalf of the Hellenic Sepsis Study Group BMC
Completed study Official Study Title Prospective Multi-centre Clinical Study to Assess the Clinical Validity of the Heparin Binding Protein Assay to Indicate the Presence and Outcome of Sepsis in Patients With Suspected Infection Following Emergency Department Admission Brief Description PROMPT is a non-interventional trial aiming to validate the diagnostic accuracy of Heparin Binding Protein
Nikolaos Antonakos, Thomas Tsaganos, Volker Oberle, Iraklis Tsangaris, Malvina Lada, Aikaterini Pistiki, Nikolaos Machairas, Maria Souli, Michael Bauer, Evangelos J. Giamarellos-Bourboulis Critical Care 2017 Mar 9;21(1):48 DOI: 10.1186/s13054-017-1625-1View article 🡇 Funding The study was funded by unrestricted educational grants provided by the Hellenic Institute for the Study of Sepsis and by the
Eleftherios Mandragos, Aikaterini Pistiki, Iraklis Tsangaris, Christina Routsi, Michael Paraschos, Dionyssia-Irene Droggiti, Olga Savvidou, Dimitrios Mastrokalos, Panayiotis J Papagelopoulos, Mihai G Netea, Evangelos J Giamarellos-Bourboulis Journal of Infection 2017 Feb;74(2):163-171 DOI: 10.1016/j.jinf.2016.10.007View the article 🡇 Funding The study was funded by the Hellenic Institute for the Study of Sepsis. Keywords: Cytokines; Interleukin-10; Multiple