hiss, Author at HISS

1 August, 2016

High Copy Numbers of β-Defensin Cluster on 8p23.1, Confer Genetic Susceptibility, and Modulate the Physical Course of Hidradenitis Suppurativa/Acne Inversa

2023-01-16T01:28:08+03:00By hiss|Categories: Publications|Tags: Hidradenitis suppurativa, PhD|

Evangelos J. Giamarellos-Bourboulis, Matthias Platzer, Ioannis Karagiannidis, Theodora Kanni, Georgios Nikolakis, Jens Ulrich, Michael Bellutti, Harald Gollnick, Michael Bauer, Christos C Zouboulis, Klaus Huse Journal of Investigative Dermatology 2016 Aug;136(8):1592-1598 DOI: 10.1016/j.jid.2016.04.021View article ???? Funding The study was funded in part by the Hellenic Institute for the Study of Sepsis and by

1 July, 2016

Polymorphisms of cystathionine beta-synthase gene are associated with susceptibility to sepsis

2023-02-16T15:22:55+03:00By hiss|Categories: Genetics, Publications|Tags: genetics, Sepsis|

Christoph Sponholz, Marcel Kramer, Franziska Schöneweck, Uwe Menzel, Kolsoum Inanloo Rahatloo, Evangelos J. Giamarellos-Bourboulis, Vassileios Papavassileiou, Korina Lymberopoulou, Maria Pavlaki, Ioannis Koutelidakis, Ioannis Perdios, André Scherag, Michael Bauer, Matthias Platzer, Klaus Huse European Journal of Human Genetics 2016 Jul;24(7):1041-8 DOI 10.1038/ejhg.2015.231View article 🡇 Funding This work was supported by the Federal Ministry of

1 June, 2016

Improving outcomes of severe infections by multidrug-resistant pathogens with polyclonal IgM-enriched immunoglobulins

2024-03-28T15:26:10+03:00By hiss|Categories: Pathogenesis, Publications|Tags: Sepsis|

Evangelos J. Giamarellos-Bourboulis, Nikolaos Tziolos, Christina Routsi, Chrysostomos Katsenos, Iraklis Tsangaris, Ioannis Pneumatikos, Glykeria Vlachogiannis, Vasiliki Theodorou, Athanasios Prekates, Elli Antypa, Vasilios Koulouras, Nikolaos Kapravelos, Charalambos Gogos, Eleni Antoniadou, Konstantinos Mandragos, Apostolos Armaganidis; Hellenic Sepsis Study Group Clinical Microbiology and Infection 2016 Jun;22(6):499-506 DOI 10.1016/j.cmi.2016.01.021Download pdf 🡇 Funding The study was supported

23 May, 2016

Clarithromycin Leads to Long-Term Survival and Cost Benefit in Ventilator-Associated Pneumonia and Sepsis

2023-02-16T15:31:14+03:00By hiss|Categories: Other Grants, Publications|Tags: clarithromycin, Sepsis|

Thomas Tsaganos, Maria Raftogiannis, Maria Pratikaki, Sofia Christodoulou, Anastasia Kotanidou, Evangelos Papadomichelakis, Apostolos Armaganidis, Christina Routsi, Evangelos J. Giamarellos-Bourboulis Antimicrobial Agents and Chemotherapy 2016 May 23;60(6):3640-6 DOI: 10.1128/AAC.02974-15View article 🡇 Funding The study was funded by the Hellenic Institute for the Study of Sepsis. Keywords: pneumonia; sepsis

1 April, 2016

Individualized significance of the -251 A/T single nucleotide polymorphism of interleukin-8 in severe infections

2023-02-16T15:31:36+03:00By hiss|Categories: Genetics, Publications|Tags: genetics, Sepsis|

Marianna Georgitsi, Vasileios Vitoros, Charalambos Panou, Iraklis Tsangaris, Eleni Aimoniotou, Nikolaos K Gatselis, Eleftheria Chasou, George Kouliatsis, Konstantinos Leventogiannis, Dimitrios Velissaris, Eleni Belesiotou, Dioritou-Aggaliadou O, Efthymia Giannitsioti, Mihai G Netea, Evangelos J. Giamarellos-Bourboulis, George Giannikopoulos, Zoi Alexiou, Nikolaos Voloudakis, Antonia Koutsoukou; Hellenic Sepsis Study Group European Journal of Clinical Microbiology & Infectious Diseases

1 April, 2016

A Transcriptomic Biomarker to Quantify Systemic Inflammation in Sepsis – A Prospective Multicenter Phase II Diagnostic Study

2024-03-28T15:15:23+03:00By hiss|Categories: Biomarkers, Publications|Tags: Sepsis, transcriptomics|

Michael Bauer, Evangelos J. Giamarellos-Bourboulis, Andreas Kortgen, Eva Möller, Karen Felsmann, Jean Marc Cavaillon, Orlando Guntinas-Lichius, Olivier Rutschmann, Andriy Ruryk, Matthias Kohl, Britta Wlotzka, Stefan Rußwurm, John C Marshall, Konrad Reinhart eBioMedicine 2016 Apr;6:114-125 DOI: 10.1016/j.ebiom.2016.03.006Download pdf 🡇 Funding The works were supported by the BMBF within the framework of the “MetaZIK”/ZIK Septomics

1 January, 2016

Safety and Efficacy of Anakinra in Severe Hidradenitis Suppurativa: A Randomized Clinical Trial

2023-02-16T15:33:15+03:00By hiss|Categories: Publications|Tags: Anakinra, clinical trial, Hidradenitis suppurativa, PhD|

Vassiliki Tzanetakou, Theodora Kanni, Sophia Giatrakou, Alexandros Katoulis, Evangelia Papadavid, Mihai G Netea, Charles A Dinarello, Jos W M van der Meer, Dimitrios Rigopoulos, Evangelos J. Giamarellos-Bourboulis JAMA Dermatology 2016 Jan;152(1):52-59 DOI: 10.1001/jamadermatol.2015.3903View article 🡇 Funding This study was supported in part by the Interleukin Foundation, by grant AI-15614 from the National Institutes

1 December, 2015

Defective cytokine production early after multiple traumas: Modulation in severe sepsis

2023-02-16T15:33:38+03:00By hiss|Categories: Other Grants, Publications|Tags: PhD, Sepsis|

Michael D Paraschos, Maria Patrani, Aikaterini Pistiki, Chrysostomos Katsenos, Thomas Tsaganos, Mihai G Netea,, Evangelos J. Giamarellos-Bourboulis, Konstantinos Mandragos Cytokine 2015 Dec;76(2):222-226 DOI: 10.1016/j.cyto.2015.05.021View article 🡇 Funding The study was funded by the Hellenic Institute for the Study of Sepsis. Keywords: Cytokines; Endotoxins; Outcome; Severe sepsis; Trauma

1 December, 2015

In Vitro Activity of Oral Cephalosporins (Cefprozil and Cefixime) Against Ciprofloxacin-Resistant Enterobacteriaceae from Community-Acquired Urinary-Tract Infections

2023-02-16T15:34:29+03:00By hiss|Categories: Other Grants, Publications|Tags: PhD|

Aikaterini Pistiki, Thomas Tsaganos, Irene Galani, Evangelos J. Giamarellos-Bourboulis Infectious Diseases and Therapy 2015 Dec;4(4):425-32 DOI: 10.1007/s40121-015-0089-3View article 🡇 Funding The study was funded by a kind donation from the Hellenic Institute for the Study of Sepsis. Keywords: Cefprozil; Cefixime; Ciprofloxacin; Escherichia coli; Urinary tract;

1 December, 2015

HIDRA04

2023-01-09T12:08:13+03:00By hiss|Categories: Completed, Interventional, Studies, Systemic inflammatory disorders|Tags: Hidradenitis suppurativa|

Completed study Official Study Title A double-blind, randomised, placebo-controlled clinical trial of the safety and efficacy of MABp1, a- first-in-class true human antibody targeting interleukin-1alpha, in patients with hidradenitis suppurativa not eligible for adalimumab Brief Description HIDRA04 is a double-blind randomized study aiming to the comparison of the efficacy of MABp1 (Bermekimab), a fully

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