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So far hiss has created 183 blog entries.
1 September, 2017

PROMPT

2023-01-09T12:10:01+03:00By |Categories: Completed, Non-Interventional, Sepsis and severe infections, Studies|Tags: |

Completed study Official Study Title Prospective Multi-centre Clinical Study to Assess the Clinical Validity of the Heparin Binding Protein Assay to Indicate the Presence and Outcome of Sepsis in Patients With Suspected Infection Following Emergency Department Admission Brief Description PROMPT is a non-interventional trial aiming to validate the diagnostic accuracy of Heparin Binding Protein

9 March, 2017

Decreased cytokine production by mononuclear cells after severe gram-negative infections: early clinical signs and association with final outcome

2023-02-16T15:14:13+03:00By |Categories: Other Grants, Publications|Tags: |

Nikolaos Antonakos, Thomas Tsaganos, Volker Oberle, Iraklis Tsangaris, Malvina Lada, Aikaterini Pistiki, Nikolaos Machairas, Maria Souli, Michael Bauer, Evangelos J. Giamarellos-Bourboulis Critical Care 2017 Mar 9;21(1):48 DOI: 10.1186/s13054-017-1625-1View article 🡇 Funding The study was funded by unrestricted educational grants provided by the Hellenic Institute for the Study of Sepsis and by the

1 February, 2017

Survival after multiple traumas is associated with improved outcomes from gram-negative sepsis: Clinical and experimental evidence

2023-02-16T15:16:38+03:00By |Categories: Pathogenesis, Publications|Tags: |

Eleftherios Mandragos, Aikaterini Pistiki, Iraklis Tsangaris, Christina Routsi, Michael Paraschos, Dionyssia-Irene Droggiti, Olga Savvidou, Dimitrios Mastrokalos, Panayiotis J Papagelopoulos, Mihai G Netea, Evangelos J Giamarellos-Bourboulis Journal of Infection 2017 Feb;74(2):163-171 DOI: 10.1016/j.jinf.2016.10.007View the article 🡇 Funding The study was funded by the Hellenic Institute for the Study of Sepsis. Keywords: Cytokines; Interleukin-10; Multiple

1 February, 2017

Validation of the new Sepsis-3 definitions: proposal for improvement in early risk identification

2024-03-28T16:25:20+03:00By |Categories: Epidemiology, Publications|Tags: |

E.J. Giamarellos-Bourboulis, T. Tsaganos, I. Tsangaris, M. Lada, C. Routsi, D. Sinapidis, M. Koupetori, M. Bristianou, G. Adamis, K. Mandragos, G.N. Dalekos, I. Kritselis, G. Giannikopoulos, I. Koutelidakis, M. Pavlaki, E. Antoniadou, G. Vlachogiannis, V. Koulouras, A. Prekates, G. Dimopoulos, A. Koutsoukou, I. Pnevmatikos, A. Ioakeimidou, A. Kotanidou, S.E. Orfanos, A. Armaganidis, C. Gogos,

1 December, 2016

IFX-1-P2.3

2023-01-09T12:08:40+03:00By |Categories: Completed, Interventional, Studies, Systemic inflammatory disorders|Tags: |

Completed study Official Study Title An Open Label Phase II Trial to Evaluate the Safety of IFX-1 in Patients With Moderate to Severe Hidradenitis Suppurativa Details Status: Completed Study Type: Interventional (Clinical Trial) Study phase: II Study sites:  1 site in Greece Actual enrolment: 12 participants ClinicalTrials.gov Identifier: NCT03001622 EudraCT number: 2016-002988-33 National

1 November, 2016

Change of annexin binding of monocytes as an expression of cellular response to Candida albicans: down-regulation in severe sepsis

2023-02-16T15:17:58+03:00By |Categories: Other Grants, Publications|Tags: , , |

Aikaterini Pistiki, Thomas Tsaganos, Iraklis Tsangaris, Nikolaos Antonakos, Georgia Damoraki, Evangelos J. Giamarellos-Bourboulis European Journal of Clinical Microbiology and Infectious Diseases 2016 Nov;35(11):1787-1793 DOI: 10.1007/s10096-016-2728-3View article 🡇 Funding The study was funded by the Hellenic Institute for the Study of Sepsis. Keywords: Sepsis; immunology

1 November, 2016

Soluble urokinase plasminogen activator receptor informs on the progression course after multiple injuries

2023-02-16T15:18:46+03:00By |Categories: Publications|Tags: , |

Maria Patrani, Thomas Tsaganos, Katerina Kotzampassi, Michael Paraschos, Chrysostomos Katsenos, Evangelos J. Giamarellos-Bourboulis, Konstantinos Mandragos Biomarkers 2016 Nov;21(7):660-4 DOI 10.1016/j.cyto.2022.15611 View article 🡇 Funding The study was funded in part by (a) the Hellenic Institute for the Study of Sepsis; and (b) an unrestricted educational grant by ViroGates SA, Copenhagen,

1 October, 2016

Systemic over-release of interleukin-17 in acute kidney injury after septic shock: Clinical and experimental evidence

2023-02-16T15:19:12+03:00By |Categories: Other Grants, Publications|Tags: , |

Panagiota Maravitsa, Maria Adamopoulou, Aikaterini Pistiki, Mihai G Netea, Konstantinos Louis, Evangelos J. Giamarellos-Bourboulis Immunology Letters 2016 Oct;178:68-76 DOI: 10.1016/j.imlet.2016.08.002View article 🡇 Funding The study was funded by the Hellenic Institute for the Study of Sepsis. MGN was supported by the #310372 European Research Council Consolidator Grant. Keywords: Acute kidney injury; Interleukin-17;

1 October, 2016

Genetic Factors of the Disease Course after Sepsis: A Genome-Wide Study for 28 Day Mortality

2024-03-28T16:06:39+03:00By |Categories: Genetics, Publications|Tags: , |

André Scherag, Franziska Schöneweck, Miriam Kesselmeier, Stefan Taudien, Matthias Platzer, Marius Felder, Christoph Sponholz, Anna Rautanen, Adrian V S Hill, Charles J Hinds, Hamid Hossain, Norbert Suttorp, Oliver Kurzai, Hortense Slevogt, Evangelos J. Giamarellos-Bourboulis, , Apostolos Armaganidis, Evelyn Trips, Markus Scholz, Frank M Brunkhorst eBioMedicine 2016 Oct;12:239-246 DOI 10.1016/j.ebiom.2016.08.043Download pdf 🡇 Funding The

1 October, 2016

Genetic Factors of the Disease Course After Sepsis: Rare Deleterious Variants Are Predictive

2024-03-28T15:43:00+03:00By |Categories: Genetics, Publications|Tags: , |

Stefan Taudien, Ludwig Lausser, Evangelos J. Giamarellos-Bourboulis, Christoph Sponholz, Franziska Schöneweck, Marius Felder, Lyn-Rouven Schirra, Florian Schmid, Charalambos Gogos, Susann Groth, Britt-Sabina Petersen, Andre Franke, Wolfgang Lieb, Klaus Huse, Peter F Zipfel, Oliver Kurzai, Barbara Moepps, Peter Gierschik, Michael Bauer, André Scherag, Hans A Kestler, Matthias Platzer eBioMedicine 2016 Oct;12:227-238 DOI 10.1016/j.ebiom.2016.08.037

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