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So far hiss has created 183 blog entries.
1 December, 2015

Defective cytokine production early after multiple traumas: Modulation in severe sepsis

2023-02-16T15:33:38+03:00By |Categories: Other Grants, Publications|Tags: , |

Michael D Paraschos, Maria Patrani, Aikaterini Pistiki, Chrysostomos Katsenos, Thomas Tsaganos, Mihai G Netea,, Evangelos J. Giamarellos-Bourboulis, Konstantinos Mandragos Cytokine 2015 Dec;76(2):222-226 DOI: 10.1016/j.cyto.2015.05.021View article 🡇 Funding The study was funded by the Hellenic Institute for the Study of Sepsis. Keywords: Cytokines; Endotoxins; Outcome; Severe sepsis; Trauma

1 December, 2015

In Vitro Activity of Oral Cephalosporins (Cefprozil and Cefixime) Against Ciprofloxacin-Resistant Enterobacteriaceae from Community-Acquired Urinary-Tract Infections

2023-02-16T15:34:29+03:00By |Categories: Other Grants, Publications|Tags: |

Aikaterini Pistiki, Thomas Tsaganos, Irene Galani, Evangelos J. Giamarellos-Bourboulis Infectious Diseases and Therapy 2015 Dec;4(4):425-32 DOI: 10.1007/s40121-015-0089-3View article 🡇 Funding The study was funded by a kind donation from the Hellenic Institute for the Study of Sepsis. Keywords: Cefprozil; Cefixime; Ciprofloxacin; Escherichia coli; Urinary tract;

1 December, 2015

HIDRA04

2023-01-09T12:08:13+03:00By |Categories: Completed, Interventional, Studies, Systemic inflammatory disorders|Tags: |

Completed study Official Study Title A double-blind, randomised, placebo-controlled clinical trial of the safety and efficacy of MABp1, a- first-in-class true human antibody targeting interleukin-1alpha, in patients with hidradenitis suppurativa not eligible for adalimumab Brief Description HIDRA04 is a double-blind randomized study aiming to the comparison of the efficacy of MABp1 (Bermekimab), a fully

1 December, 2015

-572 G/C single nucleotide polymorphism of interleukin-6 and sepsis predisposition in chronic renal disease

2023-02-16T15:34:49+03:00By |Categories: Genetics, Publications|Tags: , |

Andreas Panayides, Aikaterini Ioakeimidou, Vasileios Karamouzos, Nikolaos Antonakos, Ioannis Koutelidakis, George Giannikopoulos, Konstantinos Makaritsis, Nikolaos Voloudakis, Konstantinos Toutouzas, Nikoletta Rovina, Magdalini Bristianou, Georgia Damoraki, Christina Routsi, Evangelos J. Giamarellos-Bourboulis; Hellenic Sepsis Study Group European Journal of Clinical Microbiology & Infectious Diseases 2015 Dec;34(12):2439-46 DOI 10.1007/s10096-015-2500-0View article 🡇 Funding The study was supported by

1 December, 2015

Effects of the 34C>T Variant of the AMPD1 Gene on Immune Function, Multi-Organ Dysfunction, and Mortality in Sepsis Patients

2023-02-16T15:35:10+03:00By |Categories: Genetics, Publications|Tags: , |

Bart P Ramakers, Evangelos J. Giamarellos-Bourboulis, Chronis Tasioudis, Marieke J H Coenen, Matthijs Kox, Sita H Vermeulen, Johanne M Groothuismink, Johannes G van der Hoeven, Christina Routsi, Athina Savva, Athanassios Prekates, Filia Diamantea, Dimitrios Sinapidis, Paul Smits, Konstantinos Toutouzas, Niels P Riksen, Peter Pickkers; Hellenic Sepsis Study Group Shock 2015 Dec;44(6):542-7 DOI 10.1097/SHK.0000000000000456

1 November, 2015

Interactions of Klebsiella pneumoniae with the innate immune system vary in relation to clone and resistance phenotype

2023-02-16T15:35:31+03:00By |Categories: Other Grants, Publications|Tags: , |

Iliana-Maria Pantelidou, Irene Galani, Marianna Georgitsi, George L Daikos, Evangelos J. Giamarellos-Bourboulis Antimicrobial Agents and Chemotherapy 2015 Nov;59(11):7036-43 DOI: 10.1128/AAC.01405-15View article 🡇 Funding This study was supported by the Hellenic Institute for the Study of Sepsis. Keywords: Klebsiella pneumoniae

1 October, 2015

SPECIFY

2023-01-09T12:09:35+03:00By |Categories: Completed, Non-Interventional, Sepsis and severe infections, Studies|Tags: |

Completed study Official Study Title Scoring PErsonalized needs in Clostridium difficile Infections for Fidaxomixin therapY Brief Description The SPECIFY study is a non-interventional study aiming to develop a complex score composed by clinical data, genomic data and protein biomarkers to early predict patients with infection by Clostridium difficile at high likelihood to develop organ

19 June, 2015

Compartmentalized Cytokine Responses in Hidradenitis Suppurativa

2023-02-16T15:36:00+03:00By |Categories: Publications|Tags: , |

Theodora Kanni, Vassiliki Tzanetakou, Athina Savva, Brigit Kersten, Aikaterini Pistiki, Frank L van de Veerdonk, Mihai G Netea, Jos W van der Meer, Evangelos J. Giamarellos-Bourboulis PLoS One 2015 Jun 19;10(6):e0130522 DOI: 10.1371/journal.pone.0130522View article 🡇 Funding The study was funded by the Hellenic Institute for the Study of Sepsis. MGN was funded by

1 May, 2015

Angiopoietin-2 associations with the underlying infection and sepsis severity

2023-02-16T15:36:31+03:00By |Categories: Publications|Tags: |

Korina Lymperopoulou, Dimitrios Velissaris, Antigone Kotsaki, Elli Antypa, Sara Georgiadou, Thomas Tsaganos, Despina Koulenti, Evgenia Paggalou, Georgia Damoraki, Napoleon Karagiannidis, Stylianos E Orfanos Cytokine 2015 May;73(1):163-8 DOI: 10.1016/j.cyto.2015.01.022View article 🡇 Funding This study was funded by the Hellenic Institute for the Study of Sepsis. Keywords: Angiopoietin-2; Infection; Organ failure; Sepsis

1 April, 2015

Endotoxemia as a diagnostic tool for patients with suspected bacteremia caused by gram-negative organisms: a meta-analysis of 4 decades of studies

2023-02-16T15:37:11+03:00By |Categories: Biomarkers, Publications|Tags: |

James C Hurley, Piotr Nowak, Lars Öhrmalm, Charalambos Gogos, Apostolos Armaganidis, Evangelos J. Giamarellos-Bourboulis Journal of Clinical Microbiology 2015 Apr;53(4):1183-91 DOI: 10.1128/JCM.03531-14 View article 🡇 FundingThis research was supported by the Australian Government Department of Health and Ageing through the Rural Clinical Training and Support program. Keywords: Endotoxemia; Bacteremia

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