hiss, Author at HISS

15 January, 2021

Procalcitonin to Reduce Long-Term Infection-associated Adverse Events in Sepsis. A Randomized Trial

2024-03-29T14:03:16+03:00By hiss|Categories: Publications, Therapeutics|Tags: clinical trial, procalcitonin, Sepsis|

Evdoxia Kyriazopoulou, Lydia Liaskou-Antoniou, George Adamis, Antonia Panagaki, Nikolaos Melachroinopoulos, Elina Drakou, Konstantinos Marousis, Georgios Chrysos, Andronikos Spyrou, Nikolaos Alexiou, Styliani Symbardi, Zoi Alexiou, Styliani Lagou, Virginia Kolonia, Theologia Gkavogianni, Miltiades Kyprianou, Ioannis Anagnostopoulos, Garyfallia Poulakou, Malvina Lada, Anna Makina, Efrosyni Roulia, Marina Koupetori, Vasileios Apostolopoulos, Dimitra Petrou, Thomas Nitsotolis, Anastasia Antoniadou, Evangelos J.

13 January, 2021

Disease severity-specific neutrophil signatures in blood transcriptomes stratify COVID-19 patients

2023-02-16T13:35:55+03:00By hiss|Categories: Genetics, Publications|Tags: COVID-19, genetics|

Anna C Aschenbrenner, Maria Mouktaroudi, Benjamin Krämer, Marie Oestreich, Nikolaos Antonakos, Melanie Nuesch-Germano, Konstantina Gkizeli, Lorenzo Bonaguro, Nico Reusch, Kevin Baßler, Maria Saridaki, Rainer Knoll, Tal Pecht, Theodore S Kapellos, Sarandia Doulou, Charlotte Kröger, Miriam Herbert, Lisa Holsten, Arik Horne, Ioanna D Gemünd, Nikoletta Rovina, Shobhit Agrawal, Kilian Dahm, Martina van Uelft, Anna Drews,

1 January, 2021

ACCESS

2024-02-07T15:52:51+03:00By hiss|Categories: Completed, Interventional, Sepsis and severe infections, Studies|Tags: clarithromycin, pneumonia|

Completed study Official Study Title A randomized clinical trial of oral Clarithromycin in Community-acquired pneumonia to attenuatE inflammatory responseS and improve outcomeS Brief Description Based on evidence coming from observational studies that addition of macrolides in the treatment regimen of community-acquired pneumonia (CAP) exhibits some anti-inflammatory mode of action, this RCT is aiming to

1 January, 2021

Diabetes on sepsis outcomes in non-ICU patients: A cohort study and review of the literature

2023-02-16T13:36:16+03:00By hiss|Categories: Biomarkers, Publications|Tags: diabetes, Sepsis|

Karolina Akinosoglou, Georgia Kapsokosta, Maria Mouktaroudi, Nikoletta Rovina, Vassileios Kaldis, Aggelos Stefos, Marina Kontogiorgi, Evangelos J. Giamarellos-Bourboulis, Charalambos Gogos, Hellenic Sepsis Study Group Journal of Diabetes and Its Complications 2021 Jan;35(1):107765 DOI: 10.1016/j.jdiacomp.2020.107765View article 🡇 Funding The works were supported by the BMBF within the framework of the “MetaZIK”/ZIK Septomics Jena (03Z2J521),

1 December, 2020

De-escalation of antimicrobial therapy in ICU settings with high prevalence of multidrug-resistant bacteria: a multicentre prospective observational cohort study in patients with sepsis or septic shock

2023-02-16T13:36:45+03:00By hiss|Categories: Multicenter studies in Greece, Publications|Tags: Sepsis, SOFA|

Christina Routsi, Aikaterini Gkoufa, Kostoula Arvaniti, Stelios Kokkoris, Alexandros Tourtoglou, Vassiliki Theodorou, Anna Vemvetsou, Georgios Kassianidis, Athena Amerikanou, Elisabeth Paramythiotou, Efstathia Potamianou, Kyriakos Ntorlis, Angeliki Kanavou, Georgios Nakos, Eleftheria Hassou, Helen Antoniadou, Ilias Karaiskos, Athanasios Prekates, Apostolos Armaganidis, Ioannis Pnevmatikos, Miltiades Kyprianou, Spyros Zakynthinos, Garyfallia Poulakou, Helen Giamarellou Journal of Antimicrobial Chemotherapy 2020 Dec

1 December, 2020

SAVE-MORE

2024-03-14T14:28:56+03:00By hiss|Categories: Completed, Interventional, Sepsis and severe infections, Studies|Tags: Anakinra, COVID-19|

Completed study Official Study Title suPAR-guided Anakinra treatment for Validation of the risk and Early Management Of seveRE respiratory failure by COVID-19: The SAVE-MORE Double-blind, Randomized, Phase III Confirmatory Trial Brief Description SAVE-MORE is a double-blind randomized clinical trial aiming to study the early treatment of patients with COVID-19 pneumonia with anakinra guided by

19 November, 2020

A novel optical biosensor for the early diagnosis of sepsis and severe Covid-19: the PROUD study

2024-03-29T13:55:21+03:00By hiss|Categories: Biomarkers, Publications|Tags: clinical trial, COVID-19, Sepsis|

Sarantia Doulou, Konstantinos Leventogiannis, Maria Tsilika, Matthew Rodencal, Konstantina Katrini, Nikolaos Antonakos, Miltiades Kyprianou, Emmanouil Karofylakis, Athanassios Karageorgos, Panagiotis Koufargyris, Gennaios Christopoulos, George Kassianidis, Kimon Stamatelopoulos, Robert Newberry, Evangelos J. Giamarellos-Bourboulis BMC Infectious Diseases 2020 Nov 19;20(1):860 DOI: 10.1186/s12879-020-05607-1Download pdf 🡇 Funding The study was funded in part by the Hellenic Institute

1 November, 2020

Soluble Urokinase Receptor (SuPAR) in COVID-19-Related AKI

2023-02-16T13:38:04+03:00By hiss|Categories: Publications|Tags: COVID-19, suPAR|

Tariq U Azam, Husam R Shadid, Pennelope Blakely, Patrick O'Hayer, Hanna Berlin, Michael Pan, Peiyao Zhao, Lili Zhao, Subramaniam Pennathur, Rodica Pop-Busui, Izzet Altintas, Jens Tingleff, Marius A Stauning, Ove Andersen, Maria-Evangelia Adami, Nicky Solomonidi, Maria Tsilika, Pinkus Tober-Lau, Eleni Arnaoutoglou, Verena Keitel, Frank Tacke, Athanasios Chalkias, Sven H Loosen, Evangelos J. Giamarellos-Bourboulis, Jesper

1 November, 2020

Serum Hydrogen Sulfide and Outcome Association in Pneumonia by the SARS-CoV-2 Coronavirus

2024-03-29T13:45:05+03:00By hiss|Categories: Pathogenesis, Publications|Tags: COVID-19|

Georgios Renieris, Konstantina Katrini, Christina Damoulari, Karolina Akinosoglou, Christos Psarrakis, Magdalini Kyriakopoulou, George Dimopoulos, Malvina Lada, Panagiotis Koufargyris, Evangelos J. Giamarellos-Bourboulis Shock 2020 Nov;54(5):633-637 DOI: 10.1097/SHK.0000000000001562Download pdf 🡇 Funding GR is funded from the European Union’s Horizon 2020 research and innovation program under the Marie Skłodowska-Curie grant agreement grant European Sepsis Academy (agreement

1 October, 2020

SARS-CoV-2/COVID-19: Evolving Reality, Global Response, Knowledge Gaps, and Opportunities

2023-02-16T13:38:43+03:00By hiss|Categories: Publications|Tags: ARDS|

Marcin F Osuchowski, Federico Aletti, Jean-Marc Cavaillon, Stefanie B Flohé, Evangelos J. Giamarellos-Bourboulis, Markus Huber-Lang, Borna Relja, Tomasz Skirecki, Andrea Szabó, Marc Maegele Shock 2020 Oct;54(4):416-437 DOI 10.1097/SHK.0000000000001565 View article 🡇 Funding EJG-B: honoraria from AbbVie USA, Abbott CH, InflaRx GmbH, MSD Greece, XBiotech Inc. and Angelini Italy; independent educational

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