hiss, Author at HISS

1 December, 2020

De-escalation of antimicrobial therapy in ICU settings with high prevalence of multidrug-resistant bacteria: a multicentre prospective observational cohort study in patients with sepsis or septic shock

2023-02-16T13:36:45+03:00By hiss|Categories: Multicenter studies in Greece, Publications|Tags: Sepsis, SOFA|

Christina Routsi, Aikaterini Gkoufa, Kostoula Arvaniti, Stelios Kokkoris, Alexandros Tourtoglou, Vassiliki Theodorou, Anna Vemvetsou, Georgios Kassianidis, Athena Amerikanou, Elisabeth Paramythiotou, Efstathia Potamianou, Kyriakos Ntorlis, Angeliki Kanavou, Georgios Nakos, Eleftheria Hassou, Helen Antoniadou, Ilias Karaiskos, Athanasios Prekates, Apostolos Armaganidis, Ioannis Pnevmatikos, Miltiades Kyprianou, Spyros Zakynthinos, Garyfallia Poulakou, Helen Giamarellou Journal of Antimicrobial Chemotherapy 2020 Dec

1 December, 2020

SAVE-MORE

2024-03-14T14:28:56+03:00By hiss|Categories: Completed, Interventional, Sepsis and severe infections, Studies|Tags: Anakinra, COVID-19|

Completed study Official Study Title suPAR-guided Anakinra treatment for Validation of the risk and Early Management Of seveRE respiratory failure by COVID-19: The SAVE-MORE Double-blind, Randomized, Phase III Confirmatory Trial Brief Description SAVE-MORE is a double-blind randomized clinical trial aiming to study the early treatment of patients with COVID-19 pneumonia with anakinra guided by

19 November, 2020

A novel optical biosensor for the early diagnosis of sepsis and severe Covid-19: the PROUD study

2024-03-29T13:55:21+03:00By hiss|Categories: Biomarkers, Publications|Tags: clinical trial, COVID-19, Sepsis|

Sarantia Doulou, Konstantinos Leventogiannis, Maria Tsilika, Matthew Rodencal, Konstantina Katrini, Nikolaos Antonakos, Miltiades Kyprianou, Emmanouil Karofylakis, Athanassios Karageorgos, Panagiotis Koufargyris, Gennaios Christopoulos, George Kassianidis, Kimon Stamatelopoulos, Robert Newberry, Evangelos J. Giamarellos-Bourboulis BMC Infectious Diseases 2020 Nov 19;20(1):860 DOI: 10.1186/s12879-020-05607-1Download pdf 🡇 Funding The study was funded in part by the Hellenic Institute

1 November, 2020

Soluble Urokinase Receptor (SuPAR) in COVID-19-Related AKI

2023-02-16T13:38:04+03:00By hiss|Categories: Publications|Tags: COVID-19, suPAR|

Tariq U Azam, Husam R Shadid, Pennelope Blakely, Patrick O'Hayer, Hanna Berlin, Michael Pan, Peiyao Zhao, Lili Zhao, Subramaniam Pennathur, Rodica Pop-Busui, Izzet Altintas, Jens Tingleff, Marius A Stauning, Ove Andersen, Maria-Evangelia Adami, Nicky Solomonidi, Maria Tsilika, Pinkus Tober-Lau, Eleni Arnaoutoglou, Verena Keitel, Frank Tacke, Athanasios Chalkias, Sven H Loosen, Evangelos J. Giamarellos-Bourboulis, Jesper

1 November, 2020

Serum Hydrogen Sulfide and Outcome Association in Pneumonia by the SARS-CoV-2 Coronavirus

2024-03-29T13:45:05+03:00By hiss|Categories: Pathogenesis, Publications|Tags: COVID-19|

Georgios Renieris, Konstantina Katrini, Christina Damoulari, Karolina Akinosoglou, Christos Psarrakis, Magdalini Kyriakopoulou, George Dimopoulos, Malvina Lada, Panagiotis Koufargyris, Evangelos J. Giamarellos-Bourboulis Shock 2020 Nov;54(5):633-637 DOI: 10.1097/SHK.0000000000001562Download pdf 🡇 Funding GR is funded from the European Union’s Horizon 2020 research and innovation program under the Marie Skłodowska-Curie grant agreement grant European Sepsis Academy (agreement

1 October, 2020

SARS-CoV-2/COVID-19: Evolving Reality, Global Response, Knowledge Gaps, and Opportunities

2023-02-16T13:38:43+03:00By hiss|Categories: Publications|Tags: ARDS|

Marcin F Osuchowski, Federico Aletti, Jean-Marc Cavaillon, Stefanie B Flohé, Evangelos J. Giamarellos-Bourboulis, Markus Huber-Lang, Borna Relja, Tomasz Skirecki, Andrea Szabó, Marc Maegele Shock 2020 Oct;54(4):416-437 DOI 10.1097/SHK.0000000000001565 View article 🡇 Funding EJG-B: honoraria from AbbVie USA, Abbott CH, InflaRx GmbH, MSD Greece, XBiotech Inc. and Angelini Italy; independent educational

1 October, 2020

Activate: Randomized Clinical Trial of BCG Vaccination against Infection in the Elderly

2023-02-16T13:39:04+03:00By hiss|Categories: Publications|Tags: BCG, clinical trial, vaccination|

Evangelos J. Giamarellos-Bourboulis, Maria Tsilika, Simone Moorlag, Nikolaos Antonakos, Antigone Kotsaki, Jorge Domínguez-Andrés, Evdoxia Kyriazopoulou, Theologia Gkavogianni, Maria-Evangelia Adami, Georgia Damoraki, Panagiotis Koufargyris, Athanassios Karageorgos, Amalia Bolanou, Hans Koenen, Reinout van Crevel, Dionyssia-Irene Droggiti, George Renieris, Antonios Papadopoulos, Mihai G Netea Cell 2020 Oct 15;183(2):315-323 DOI: 10.1016/j.cell.2020.08.051Download pdf 🡇 Funding The study was

1 September, 2020

Prognostic Role of Soluble Urokinase Plasminogen Activator Receptor at the Emergency Department: A Position Paper by the Hellenic Sepsis Study Group

2024-03-29T13:39:01+03:00By hiss|Categories: Biomarkers, Publications|Tags: suPAR|

Dimitrios Velissaris, George Dimopoulos, John Parissis, Zoi Alexiou, Nikolaos Antonakos, Dimitrios Babalis, Styliani Gerakari, Vassileios Kaldis, Pantelis Koutoukas, Malvina Lada, Konstantinos Leventogiannis, Ioannis Pantazopoulos, Antonios Papadopoulos, Eftihia Polyzogopoulou, Charalambos Gogos, Apostolos Armaganidis, Evangelos J. Giamarellos-Bourboulis Infectious Diseases and Therapy 2020 Sep;9(3):407-416 DOI: 10.1007/s40121-020-00301-wDownload pdf 🡇 Funding The study was funded by the Hellenic

1 September, 2020

Impact of comorbidities on the performance of interferon-gamma release assay in an elderly Greek population without overt immunodeficiency

2023-02-16T13:43:48+03:00By hiss|Categories: Publications|Tags: clinical trial|

Maria Tsilika, Nikolaos Antonakos, Theologia Gkavogianni, Athanassios Karageorgos, Evdoxia Kyriazopoulou, Mihai G Netea, Evangelos J. Giamarellos-Bourboulis International Journal of Antimicrobial Agents 2020 Sep;56(3):106073 DOI 10.1016/j.ijantimicag.2020.106073 View article 🡇 Funding The ACTIVATE study was supported by an ERC Advanced Grant (#833247, to MGN). MGN was also partially supported by a Spinoza

8 July, 2020

Favorable Anakinra Responses in Severe Covid-19 Patients with Secondary Hemophagocytic Lymphohistiocytosis

2024-03-29T13:31:59+03:00By hiss|Categories: Pathogenesis, Publications|Tags: Anakinra, COVID-19|

George Dimopoulos, Quirijn de Mast, Nikolaos Markou, Maria Theodorakopoulou, Apostolos Komnos, Maria Mouktaroudi, Mihai G Netea, Themistoklis Spyridopoulos, Rebecca J Verheggen, Jacobien Hoogerwerf, Alexandra Lachana, Frank L van de Veerdonk, Evangelos J. Giamarellos-Bourboulis Cell Host & Microbe 2020 Jul 8;28(1):117-123.e1 DOI 10.1016/j.chom.2020.05.007Download pdf 🡇 Funding The study was funded in part by the

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