Genetics

17 September, 2024

Clinical Phenotyping for Prognosis and Immunotherapy Guidance in Bacterial Sepsis and COVID-19

2024-10-18T11:44:36+03:00By hiss|Categories: Genetics, Publications|Tags: COVID-19, phenotypes, Sepsis|

Eleni Karakike, Simeon Metallidis, Garyfallia Poulakou, Maria Kosmidou, Nikolaos K. Gatselis, Vasileios Petrakis, Nikoletta Rovina, Eleni Gkeka, Styliani Sympardi, Ilias Papanikolaou, Ioannis Koutsodimitropoulos, Vasiliki Tzavara, Georgios Adamis, Konstantinos Tsiakos, Vasilios Koulouras, Eleni Mouloudi, Eleni Antoniadou, Gykeria Vlachogianni, Souzana Anisoglou, Nikolaos Markou, Antonia Koutsoukou, Periklis Panagopoulos, Haralampos Milionis, George N. Dalekos, Miltiades Kyprianou, Evangelos J.

13 January, 2021

Disease severity-specific neutrophil signatures in blood transcriptomes stratify COVID-19 patients

2023-02-16T13:35:55+03:00By hiss|Categories: Genetics, Publications|Tags: COVID-19, genetics|

Anna C Aschenbrenner, Maria Mouktaroudi, Benjamin Krämer, Marie Oestreich, Nikolaos Antonakos, Melanie Nuesch-Germano, Konstantina Gkizeli, Lorenzo Bonaguro, Nico Reusch, Kevin Baßler, Maria Saridaki, Rainer Knoll, Tal Pecht, Theodore S Kapellos, Sarandia Doulou, Charlotte Kröger, Miriam Herbert, Lisa Holsten, Arik Horne, Ioanna D Gemünd, Nikoletta Rovina, Shobhit Agrawal, Kilian Dahm, Martina van Uelft, Anna Drews,

1 February, 2018

Haplotypes composed of minor frequency single nucleotide polymorphisms of the TNF gene protect from progression into sepsis: A study using the new sepsis classification

2024-03-28T17:04:25+03:00By hiss|Categories: Genetics, Publications|Tags: genetics, Sepsis|

Theodoros Retsas, Klaus Huse, Lazaros-Dimitrios Lazaridis, Niki Karampela, Michael Bauer, Matthias Platzer, Virginia Kolonia, Eirini Papageorgiou, Evangelos J. Giamarellos-Bourboulis, George Dimopoulos International Journal of Infectious Diseases 2018 Feb;67:102-106 DOI: 10.1016/j.ijid.2017.12.008Download pdf 🡇 FundingThe study was funded in part by the Hellenic Institute for the Study of Sepsis and by the Federal Ministry of

1 October, 2016

Genetic Factors of the Disease Course after Sepsis: A Genome-Wide Study for 28 Day Mortality

2024-03-28T16:06:39+03:00By hiss|Categories: Genetics, Publications|Tags: genetics, Sepsis|

André Scherag, Franziska Schöneweck, Miriam Kesselmeier, Stefan Taudien, Matthias Platzer, Marius Felder, Christoph Sponholz, Anna Rautanen, Adrian V S Hill, Charles J Hinds, Hamid Hossain, Norbert Suttorp, Oliver Kurzai, Hortense Slevogt, Evangelos J. Giamarellos-Bourboulis, , Apostolos Armaganidis, Evelyn Trips, Markus Scholz, Frank M Brunkhorst eBioMedicine 2016 Oct;12:239-246 DOI 10.1016/j.ebiom.2016.08.043Download pdf 🡇 Funding The

1 October, 2016

Genetic Factors of the Disease Course After Sepsis: Rare Deleterious Variants Are Predictive

2024-03-28T15:43:00+03:00By hiss|Categories: Genetics, Publications|Tags: genetics, Sepsis|

Stefan Taudien, Ludwig Lausser, Evangelos J. Giamarellos-Bourboulis, Christoph Sponholz, Franziska Schöneweck, Marius Felder, Lyn-Rouven Schirra, Florian Schmid, Charalambos Gogos, Susann Groth, Britt-Sabina Petersen, Andre Franke, Wolfgang Lieb, Klaus Huse, Peter F Zipfel, Oliver Kurzai, Barbara Moepps, Peter Gierschik, Michael Bauer, André Scherag, Hans A Kestler, Matthias Platzer eBioMedicine 2016 Oct;12:227-238 DOI 10.1016/j.ebiom.2016.08.037

1 July, 2016

Polymorphisms of cystathionine beta-synthase gene are associated with susceptibility to sepsis

2023-02-16T15:22:55+03:00By hiss|Categories: Genetics, Publications|Tags: genetics, Sepsis|

Christoph Sponholz, Marcel Kramer, Franziska Schöneweck, Uwe Menzel, Kolsoum Inanloo Rahatloo, Evangelos J. Giamarellos-Bourboulis, Vassileios Papavassileiou, Korina Lymberopoulou, Maria Pavlaki, Ioannis Koutelidakis, Ioannis Perdios, André Scherag, Michael Bauer, Matthias Platzer, Klaus Huse European Journal of Human Genetics 2016 Jul;24(7):1041-8 DOI 10.1038/ejhg.2015.231View article 🡇 Funding This work was supported by the Federal Ministry of

1 April, 2016

Individualized significance of the -251 A/T single nucleotide polymorphism of interleukin-8 in severe infections

2023-02-16T15:31:36+03:00By hiss|Categories: Genetics, Publications|Tags: genetics, Sepsis|

Marianna Georgitsi, Vasileios Vitoros, Charalambos Panou, Iraklis Tsangaris, Eleni Aimoniotou, Nikolaos K Gatselis, Eleftheria Chasou, George Kouliatsis, Konstantinos Leventogiannis, Dimitrios Velissaris, Eleni Belesiotou, Dioritou-Aggaliadou O, Efthymia Giannitsioti, Mihai G Netea, Evangelos J. Giamarellos-Bourboulis, George Giannikopoulos, Zoi Alexiou, Nikolaos Voloudakis, Antonia Koutsoukou; Hellenic Sepsis Study Group European Journal of Clinical Microbiology & Infectious Diseases

1 December, 2015

-572 G/C single nucleotide polymorphism of interleukin-6 and sepsis predisposition in chronic renal disease

2023-02-16T15:34:49+03:00By hiss|Categories: Genetics, Publications|Tags: genetics, Sepsis|

Andreas Panayides, Aikaterini Ioakeimidou, Vasileios Karamouzos, Nikolaos Antonakos, Ioannis Koutelidakis, George Giannikopoulos, Konstantinos Makaritsis, Nikolaos Voloudakis, Konstantinos Toutouzas, Nikoletta Rovina, Magdalini Bristianou, Georgia Damoraki, Christina Routsi, Evangelos J. Giamarellos-Bourboulis; Hellenic Sepsis Study Group European Journal of Clinical Microbiology & Infectious Diseases 2015 Dec;34(12):2439-46 DOI 10.1007/s10096-015-2500-0View article 🡇 Funding The study was supported by

1 December, 2015

Effects of the 34C>T Variant of the AMPD1 Gene on Immune Function, Multi-Organ Dysfunction, and Mortality in Sepsis Patients

2023-02-16T15:35:10+03:00By hiss|Categories: Genetics, Publications|Tags: genetics, Sepsis|

Bart P Ramakers, Evangelos J. Giamarellos-Bourboulis, Chronis Tasioudis, Marieke J H Coenen, Matthijs Kox, Sita H Vermeulen, Johanne M Groothuismink, Johannes G van der Hoeven, Christina Routsi, Athina Savva, Athanassios Prekates, Filia Diamantea, Dimitrios Sinapidis, Paul Smits, Konstantinos Toutouzas, Niels P Riksen, Peter Pickkers; Hellenic Sepsis Study Group Shock 2015 Dec;44(6):542-7 DOI 10.1097/SHK.0000000000000456

23 December, 2014

Early changes of the kinetics of monocyte trem-1 reflect final outcome in human sepsis

2023-02-16T15:37:58+03:00By hiss|Categories: Genetics, Publications|Tags: genetics, Sepsis|

Androniki Marioli, Marina Koupetori, Maria Raftogiannis, Maria Patrani, Nikolaos Antonakos, Maria Pavlaki, Georgios Adamis, Georgia Dougekou, Georgia Damoraki, Iraklis Tsangaris BMC Immunology 2014 Dec 23;15:585 DOI: 10.1186/s12865-014-0063-yView article 🡇 Funding The study was supported by a kind donation form the Hellenic Institute for the Study of Sepsis. Keywords: Sepsis; Outcome; TREM-1; sTREM-1;