Publications2023-02-15T20:23:19+03:00
Support of publications

Based on its mission, the Hellenic Institute for the Study of Sepsis is supporting three types of publications of manuscripts:
a) manuscripts of the Hellenic Sepsis Study Group;
b) manuscripts on hidradenitis suppurativa; and
c) manuscripts on sepsis.
Support is provided to both pre-clinical and clinical studies and involves the expenses for personnel and consumables.
A list of supported publications is provided below.

The majority of manuscripts published by the Hellenic Sepsis Study Group, are coming from the registry of patients that has started in 2006 and that has been approved by the Ethics Committees of the hospitals (details on Ethical Approval are provided on the Methods section of each manuscript).

The manuscripts are classified by research topic. When the copyright belongs to the authors the entire pdf is given for free or else the manuscript is linked to the PubMed respective site.

Our Library

Early treatment of COVID-19 with anakinra guided by soluble urokinase plasminogen receptor plasma levels: a double-blind, randomized controlled phase 3 trial
Publication in Nature Medicine
From the related study SAVE-MORE to the approval of the study drug by EMA and FDA
More details
1May, 2022

ESCAPE: An Open-Label Trial of Personalized Immunotherapy in Critically ill COVID-19 Patients

By |May 1st, 2022|Categories: Publications, Therapeutics|Tags: , , |

Eleni Karakike, George N Dalekos, Ioannis Koutsodimitropoulos, Maria Saridaki, Chryssa Pourzitaki, Georgios Papathanakos, Antigone Kotsaki, Stamatios Chalvatzis, Vasiliki Dimakopoulou, Nikolaos Vechlidis, Elisabeth Paramythiotou, Christina Avgoustou, Aikaterini Ioakeimidou, Elli Kouriannidi, Apostolos Komnos, Evangelia Neou, Nikoletta Rovina, Eleni Stefanatou, Haralampos Milionis, George Nikolaidis, Antonia Koutsoukou, Georgia Damoraki, George Dimopoulos, Vassileios Zoumpos, Jesper Eugen-Olsen, Karolina Akinosoglou, Nikolaos

28April, 2022

Calprotectin and Imbalances between Acute-Phase Mediators Are Associated with Critical Illness in COVID-19

By |April 28th, 2022|Categories: Publications|Tags: |

Georgios Kassianidis, Athanasios Siampanos, Garyphalia Poulakou, George Adamis, Aggeliki Rapti, Haralampos Milionis, George N Dalekos, Vasileios Petrakis, Styliani Sympardi, Symeon Metallidis, Zoi Alexiou, Theologia Gkavogianni, Evangelos J. Giamarellos-Bourboulis, Theoharis C Theoharides International Journal of Molecular Sciences 2022 Apr 28;23(9):4894 DOI: 10.3390/ijms23094894 View article 🡇 Funding All reagent kits were provided

9March, 2022

Antimicrobial Stewardship Using Biomarkers: Accumulating Evidence for the Critically Ill

By |March 9th, 2022|Categories: Publications|Tags: , |

Evdoxia Kyriazopoulou, Evangelos J. Giamarellos-Bourboulis Antibiotics 2022 Mar 9;11(3):367 DOI: 10.3390/antibiotics11030367 View article 🡇 Funding This study was funded by the Hellenic Institute for the Study of Sepsis. Keywords: C-reactive protein; COVID-19; ICU; antimicrobial stewardship; biomarker; guided antimicrobial therapy; infection; presepsin; procalcitonin; sepsis

25February, 2022

Development and validation of SCOPE score: A clinical score to predict COVID-19 pneumonia progression to severe respiratory failure

By |February 25th, 2022|Categories: Publications|Tags: , , |

Evangelos J. Giamarellos-Bourboulis, Garyfallia Poulakou, Aline de Nooijer, Haralampos Milionis, Simeon Metallidis, Michalis Ploumidis, Pinelopi Grigoropoulou, Aggeliki Rapti, Francesco Vladimiro Segala, Evangelos Balis, Efthymia Giannitsioti, Paola Rodari, Ilias Kainis, Zoi Alexiou, Emanuele Focà, Brollo Lucio, Nikoletta Rovina, Laura Scorzolini, Maria Dafni, Sofia Ioannou, Alessandro Tomelleri, Katerina Dimakou, Glykeria Tzatzagou, Maria Chini, Matteo Bassetti, Christina

1December, 2021

Early Start of Oral Clarithromycin Is Associated with Better Outcome in COVID-19 of Moderate Severity: The ACHIEVE Open-Label Single-Arm Trial

By |December 1st, 2021|Categories: Publications|Tags: , , |

Konstantinos Tsiakos, Antonios Tsakiris, Georgios Tsibris, Pantazis-Michael Voutsinas, Periklis Panagopoulos, Maria Kosmidou, Vasileios Petrakis, Areti Gravvani, Theologia Gkavogianni, Eleftherios Klouras, Konstantina Katrini, Panagiotis Koufargyris, Iro Rapti, Athanassios Karageorgos, Emmanouil Vrentzos, Christina Damoulari, Vagia Zarkada, Chrysanthi Sidiropoulou, Sofia Artemi, Anastasios Ioannidis, Androniki Papapostolou, Evangelos Michelakis, Maria Georgiopoulou, Dimitra-Melia Myrodia, Panteleimon Tsiamalos, Konstantinos Syrigos, George Chrysos,

1October, 2021

Early treatment of COVID-19 with anakinra guided by soluble urokinase plasminogen receptor plasma levels: a double-blind, randomized controlled phase 3 trial

By |October 1st, 2021|Categories: Multicenter studies in Greece, Publications, Therapeutics|Tags: , , |

Evdoxia Kyriazopoulou, Garyfallia Poulakou, Haralampos Milionis, Simeon Metallidis, Georgios Adamis, Konstantinos Tsiakos, Archontoula Fragkou, Aggeliki Rapti, Christina Damoulari, Massimo Fantoni, Ioannis Kalomenidis, Georgios Chrysos, Andrea Angheben, Ilias Kainis, Zoi Alexiou, Francesco Castelli, Francesco Saverio Serino, Maria Tsilika, Petros Bakakos, Emanuele Nicastri, Vassiliki Tzavara, Evangelos Kostis, Lorenzo Dagna, Panagiotis Koufargyris, Katerina Dimakou, Spyridon Savvanis, Glykeria

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