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So far hiss has created 187 blog entries.
1 October, 2015

SPECIFY

2023-01-09T12:09:35+03:00By |Categories: Completed, Non-Interventional, Sepsis and severe infections, Studies|Tags: |

Completed study Official Study Title Scoring PErsonalized needs in Clostridium difficile Infections for Fidaxomixin therapY Brief Description The SPECIFY study is a non-interventional study aiming to develop a complex score composed by clinical data, genomic data and protein biomarkers to early predict patients with infection by Clostridium difficile at high likelihood to develop organ

19 June, 2015

Compartmentalized Cytokine Responses in Hidradenitis Suppurativa

2023-02-16T15:36:00+03:00By |Categories: Publications|Tags: , |

Theodora Kanni, Vassiliki Tzanetakou, Athina Savva, Brigit Kersten, Aikaterini Pistiki, Frank L van de Veerdonk, Mihai G Netea, Jos W van der Meer, Evangelos J. Giamarellos-Bourboulis PLoS One 2015 Jun 19;10(6):e0130522 DOI: 10.1371/journal.pone.0130522View article 🡇 Funding The study was funded by the Hellenic Institute for the Study of Sepsis. MGN was funded by

1 May, 2015

Angiopoietin-2 associations with the underlying infection and sepsis severity

2023-02-16T15:36:31+03:00By |Categories: Publications|Tags: |

Korina Lymperopoulou, Dimitrios Velissaris, Antigone Kotsaki, Elli Antypa, Sara Georgiadou, Thomas Tsaganos, Despina Koulenti, Evgenia Paggalou, Georgia Damoraki, Napoleon Karagiannidis, Stylianos E Orfanos Cytokine 2015 May;73(1):163-8 DOI: 10.1016/j.cyto.2015.01.022View article 🡇 Funding This study was funded by the Hellenic Institute for the Study of Sepsis. Keywords: Angiopoietin-2; Infection; Organ failure; Sepsis

1 April, 2015

Endotoxemia as a diagnostic tool for patients with suspected bacteremia caused by gram-negative organisms: a meta-analysis of 4 decades of studies

2023-02-16T15:37:11+03:00By |Categories: Biomarkers, Publications|Tags: |

James C Hurley, Piotr Nowak, Lars Öhrmalm, Charalambos Gogos, Apostolos Armaganidis, Evangelos J. Giamarellos-Bourboulis Journal of Clinical Microbiology 2015 Apr;53(4):1183-91 DOI: 10.1128/JCM.03531-14 View article 🡇 FundingThis research was supported by the Australian Government Department of Health and Ageing through the Rural Clinical Training and Support program. Keywords: Endotoxemia; Bacteremia

1 February, 2015

Serum soluble urokinase plasminogen activator receptor as a screening test for the early diagnosis of hepatocellular carcinoma

2023-02-16T15:37:33+03:00By |Categories: Other Grants, Publications|Tags: , |

Athina Chounta, Christofer Ellinas, Vassiliki Tzanetakou, Fani Pliarhopoulou, Virginia Mplani, Angelos Oikonomou, Kostantinos Leventogiannis, Evangelos J. Giamarellos-Bourboulis Liver International 2015 Feb;35(2):601-7 DOI: 10.1111/liv.12705View article 🡇 Funding This study was funded by a kind donation of the Hellenic Institute for the Study of Sepsis. Keywords: early diagnosis; hepatocellular carcinoma; suPAR

23 December, 2014

Early changes of the kinetics of monocyte trem-1 reflect final outcome in human sepsis

2023-02-16T15:37:58+03:00By |Categories: Genetics, Publications|Tags: , |

Androniki Marioli, Marina Koupetori, Maria Raftogiannis, Maria Patrani, Nikolaos Antonakos, Maria Pavlaki, Georgios Adamis, Georgia Dougekou, Georgia Damoraki, Iraklis Tsangaris BMC Immunology 2014 Dec 23;15:585 DOI: 10.1186/s12865-014-0063-yView article 🡇 Funding The study was supported by a kind donation form the Hellenic Institute for the Study of Sepsis. Keywords: Sepsis; Outcome; TREM-1; sTREM-1;

19 November, 2014

The discriminative capacity of soluble Toll-like receptor (sTLR)2 and sTLR4 in inflammatory diseases

2024-03-28T14:21:16+03:00By |Categories: Biomarkers, Publications|

Jaap Ten Oever, Matthijs Kox, Frank L van de Veerdonk, Khutso M Mothapo, Adriana Slavcovici, Tim L Jansen, Lieke Tweehuysen, Evangelos J. Giamarellos-Bourboulis, Peter M Schneeberger, Peter C Wever, Monique Stoffels, Anna Simon, Jos W M van der Meer, Melissa D Johnson, Bart-Jan Kullberg, Peter Pickkers, Alexandre Pachot, Leo A B Joosten, Mihai G

1 November, 2014

AIDA

2023-01-09T12:15:29+03:00By |Categories: Completed, Interventional, Sepsis and severe infections, Studies|Tags: |

Completed study Official Study Title A prospective, open label, randomized controlled clinical trial, with pharmacokinetic-pharmacodynamic validation, to compare antimicrobial treatment with oral minocycline plus rifampicin to treatment with oral linezolid for complicated skin and skin structure infections (cSSSI) caused by methicillin-resistant Staphylococcus aureus (MRSA) Brief Description The AIDA consortium is a European Consortium funded

1 August, 2014

Immunomodulatory intervention with interferon-γ in Escherichia coli pyelonephritis

2023-02-16T15:39:37+03:00By |Categories: Other Grants, Publications|Tags: |

Matthew P Katsaris, Theodoros Adamis, Aikaterini Pistiki, Dionyssia-Pinelopi Carrer, Irene Galani, Labros Sabracos, Dionyssia-Irini Droggiti, Marianna Georgitsi, Georgia Damoraki, Evangelos J. Giamarellos-Bourboulis, Michael Chrisofos Journal of Urology 2014 Aug;192(2):600-6 DOI: 10.1016/j.juro.2014.03.092View article 🡇 Funding Supported by the University of Athens Program 8161 "Kapodistrias" and the Hellenic Institute for the Study of Sepsis.

1 July, 2014

Early administration of hydrocortisone replacement after the advent of septic shock: impact on survival and immune response*

2023-02-16T16:10:25+03:00By |Categories: Pathogenesis, Publications|Tags: |

Chrysostomos S Katsenos, Anastasia N Antonopoulou, Efterpi N Apostolidou, Aikaterini Ioakeimidou, Georgia Th Kalpakou, Metaxia N Papanikolaou, Aikaterini C Pistiki, Margarita C Mpalla, Michael D Paraschos, Maria A Patrani, Maria E Pratikaki, Theodoros A Retsas, Athina A Savva, Spyridoula D Vassiliagkou, Alexandra A Lekkou, Ioanna Dimopoulou, Christina Routsi, Konstantinos E Mandragos; Hellenic Sepsis Study

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