Theodora Kanni, Maria Argyropoulou, Charles A Dinarello, John Simard, Evangelos J. Giamarellos-Bourboulis Clinical and Experimental Dermatology 2021 Jan;46(1):162-163 DOI: 10.1111/ced.14333 View article 🡇 Funding XBiotech, Texas Hellenic Sepsis Study Group Keywords: Hidradenitis Suppurativa Related Study: HIDRA04
Evangelos J. Giamarellos-Bourboulis, Mihai G Netea, Nikoletta Rovina, Karolina Akinosoglou, Anastasia Antoniadou, Nikolaos Antonakos, Georgia Damoraki, Theologia Gkavogianni, Maria-Evangelia Adami, Paraskevi Katsaounou, Maria Ntaganou, Magdalini Kyriakopoulou, George Dimopoulos, Ioannis Koutsodimitropoulos, Dimitrios Velissaris, Panagiotis Koufargyris, Athanassios Karageorgos, Konstantina Katrini, Vasileios Lekakis, Mihaela Lupse, Antigone Kotsaki, George Renieris, Danai Theodoulou, Vassiliki Panou, Evangelia Koukaki, Nikolaos Koulouris,
Completed study Official Study Title A randomized clinical trial for enhanced trained immune responses through Bacillus Calmette-Guérin vaccination to prevent infections by COVID-19 Brief Description ACTIVATE-II is a randomized clinical trial aiming to investigate if the developing concept of trained immunity i.e. the memory of the innate immune system coming after vaccination exists in
Mihai G Netea, Evangelos J. Giamarellos-Bourboulis, Jorge Domínguez-Andrés, Nigel Curtis, Reinout van Crevel, Frank L van de Veerdonk, Marc Bonten Cell 2020 May 28;181(5):969-977 DOI 10.1016/j.cell.2020.04.042 View article 🡇 Funding M.G.N. was supported by an ERC advanced grant (833247) and a Spinoza grant of the Netherlands Association for Scientific Research.
Completed study Official Study Title Anti-inflammatory ClaritHromycin to ImprovE SARS-CoV-2 (COVID-19) infection Early: The ACHIEVE open-label non-randomized clinical trial Brief Description ACHIEVE is an open non-randomized clinical trial aiming to prove that the addition of oral clarithromycin to treatment regimen of COVID-19 is associated with early clinical improvement and attenuation of the high inflammatory
Nikoletta Rovina, Karolina Akinosoglou, Jesper Eugen-Olsen, Salim Hayek, Jochen Reiser, Evangelos J. Giamarellos-Bourboulis Critical Care 2020 Apr 30;24(1):187 DOI: 10.1186/s13054-020-02897-4View article 🡇 Funding The study was funded by unrestricted educational grants provided by the Hellenic Institute for the Study of Sepsis. Funds were also provided by Rush University Medical Center. Keywords: COVID-19;
Completed study Official Study Title suPAR-guided Anakinra treatment for Validation of the risk and Early management of severe respiratory failure by COVID-19: the SAVE open-label, non-randomized single-arm trial Brief Description SAVE is an open non-randomized clinical trial aiming to study the early treatment of patients with COVID-19 pneumonia with anakinra guided by the biomarker
Completed study Official Study Title Efficiency in management of organ dysfunction associated with infection by the novel SARS-Cov-2 virus through A PErsonalized immunotherapy approach Brief Description ESCAPE is an open non-randomized clinical trial aiming to the personalized therapy of patients with COVID-19. Using biomarkers, enrolled patients are receiving treatment with intravenous anakinra or intravenous
Aspasia Liassidou, Georgios Renieris, Dionysia-Irene Droggiti, Theologia Gkavogianni, Christakis Liassides, Labros Sabracos, Evangelos J. Giamarellos-Bourboulis, Charalampos S Siristatidis American Journal of Reproductive Immunology 2020 Mar;83(3):e13216 DOI 10.1111/aji.13216 View article 🡇 Keywords: dectin-2; infection; lipopolysaccharide; miscarriage; preterm delivery
Stelios F Assimakopoulos, Karolina Akinosoglou, Anne-Lise de Lastic, Aikaterini Skintzi, Athanasia Mouzaki, Charalambos A Gogos The American Journal of the Medical Sciences 2020 Feb;359(2):100-107 DOI: 10.1016/j.amjms.2019.10.006View article 🡇 Funding The study was funded in part by the Hellenic Institute for the Study of Sepsis (98 / 9-07-2018). Keywords: Bacteremia; Endotoxemia; Gut