Biomarkers

30 April, 2020

Soluble urokinase plasminogen activator receptor (suPAR) as an early predictor of severe respiratory failure in patients with COVID-19 pneumonia

2023-02-16T14:29:21+03:00By hiss|Categories: Biomarkers, Publications|Tags: COVID-19, suPAR|

Nikoletta Rovina, Karolina Akinosoglou, Jesper Eugen-Olsen, Salim Hayek, Jochen Reiser, Evangelos J. Giamarellos-Bourboulis Critical Care 2020 Apr 30;24(1):187 DOI: 10.1186/s13054-020-02897-4View article 🡇 Funding The study was funded by unrestricted educational grants provided by the Hellenic Institute for the Study of Sepsis. Funds were also provided by Rush University Medical Center. Keywords: COVID-19;

29 November, 2019

The early change of SOFA score as a prognostic marker of 28-day sepsis mortality: analysis through a derivation and a validation cohort

2024-03-29T13:19:02+03:00By hiss|Categories: Biomarkers, Publications|Tags: Sepsis, SOFA|

Eleni Karakike, Evdoxia Kyriazopoulou, Iraklis Tsangaris, Christina Routsi, Jean-Louis Vincent, Evangelos J. Giamarellos-Bourboulis Critical Care 2019 Nov 29;23(1):387 DOI: 10.1186/s13054-019-2665-5Download pdf 🡇 Funding The study was funded by unrestricted educational grants provided by the Hellenic Institute for the Study of Sepsis and, by the Horizon 2020 Marie Skłodowska-Curie Grant European Sepsis Academy (grant

1 June, 2019

Association of the early absolute CD64-expressing neutrophil count and sepsis outcome

2023-02-16T14:34:38+03:00By hiss|Categories: Biomarkers, Other Grants, Publications|Tags: metabolism, Sepsis, SOFA|

Aggeliki Xini, Aikaterini Pistiki, Malvina Lada, Evangelos J. Giamarellos-Bourboulis, Georgios Dimopoulos European Journal of Clinical Microbiology & Infectious Diseases 2019 Jun;38(6):1123-1128 DOI: 10.1007/s10096-019-03507-0View article 🡇 FundingThe study was funded by the Hellenic Institute for the Study of Sepsis. The funders did not have any role in the study design, analysis, and interpretation of data

17 October, 2018

MicroRNAs 143 and 150 in whole blood enable detection of T-cell immunoparalysis in sepsis

2024-03-28T18:19:40+03:00By hiss|Categories: Biomarkers, Publications|Tags: miRNA, Sepsis|

Patrick Möhnle, Simon Hirschberger, Ludwig Christian Giuseppe Hinske, Josef Briegel, Max Hübner, Sebastien Weis, Georgios Dimopoulos, Michael Bauer, Evangelos J. Giamarellos-Bourboulis, Simone Kreth Molecular Medicine 2018 Oct 17;24(1):54 DOI: 10.1186/s10020-018-0056-zDownload pdf 🡇 Funding This work has been funded by the Charles-Evans-Foundation, New Jersey, USA. Sebastian Weis and Michael Bauer are supported by the

1 October, 2018

How well does qSOFA correspond to underlying systemic inflammatory response?

2023-02-16T14:38:02+03:00By hiss|Categories: Biomarkers, Publications|Tags: Sepsis, SIRS|

Karolina Akinosoglou, Spyridoula Theodoraki, Theologia Gkavogianni, Aikaterini Pistiki, Evangelos J. Giamarellos-Bourboulis, Charalambos A Gogos Cytokine 2018 Oct;110:288-290 DOI: 10.1016/j.cyto.2018.01.019View article 🡇 Funding The study was funded by the Hellenic Institute for the Study of Sepsis. Keywords: Anti-inflammatory mediators; Pro-inflammatory mediators; SIRS; Sepsis; qSOFA

1 June, 2018

Reduced circulating B cells and plasma IgM levels are associated with decreased survival in sepsis – A meta-analysis

2023-02-16T14:38:40+03:00By hiss|Categories: Biomarkers, Publications|Tags: meta-analysis, Sepsis|

Christian Krautz, Sarah L Maier, Maximilian Brunner, Melanie Langheinrich, Evangelos J. Giamarellos-Bourboulis, Charalambos Gogos, Apostolos Armaganidis, Frank Kunath, Robert Grützmann, Georg F Weber Journal of Critical Care 2018 Jun;45:71-75 DOI: 10.1016/j.jcrc.2018.01.013 View article 🡇 Keywords: Circulating B cells; Plasma IgM; Sepsis; Sepsis outcome

1 October, 2017

Increase of circulating endocan over sepsis follow-up is associated with progression into organ dysfunction

2023-02-16T15:11:50+03:00By hiss|Categories: Biomarkers, Publications|Tags: Sepsis|

Aikaterini Ioakeimidou, E Pagalou, Marina Kontogiorgi, Eleni Antoniadou, Katerina Kaziani, Konstantinos Psaroulis, Evangelos J. Giamarellos-Bourboulis, Athanasios Prekates, Nikolaos Antonakos, P Lassale, Charalambos Gogos; Hellenic Sepsis Study Group European Journal of Clinical Microbiology & Infectious Diseases 2017 Oct;36(10):1749-1756 DOI: 10.1007/s10096-017-2988-6View article 🡇 Funding The study was funded by the Hellenic Institute for the Study

1 September, 2016

Metabolite Profiles in Sepsis: Developing Prognostic Tools Based on the Type of Infection

2023-02-16T15:21:37+03:00By hiss|Categories: Biomarkers, Publications|Tags: Sepsis|

Sophie Neugebauer, Evangelos J. Giamarellos-Bourboulis, Aimilia Pelekanou, Androniki Marioli, Fotini Baziaka, Iraklis Tsangaris, Michael Bauer, Michael Kiehntopf Critical Care Medicine 2016 Sep;44(9):1649-62 DOI: 10.1097/CCM.0000000000001740 View article 🡇 FundingSupported, in part, by the framework of the German Center for Sepsis Control and Care by the Ministry of Education and Research (BMBF [via

1 April, 2016

A Transcriptomic Biomarker to Quantify Systemic Inflammation in Sepsis – A Prospective Multicenter Phase II Diagnostic Study

2024-03-28T15:15:23+03:00By hiss|Categories: Biomarkers, Publications|Tags: Sepsis, transcriptomics|

Michael Bauer, Evangelos J. Giamarellos-Bourboulis, Andreas Kortgen, Eva Möller, Karen Felsmann, Jean Marc Cavaillon, Orlando Guntinas-Lichius, Olivier Rutschmann, Andriy Ruryk, Matthias Kohl, Britta Wlotzka, Stefan Rußwurm, John C Marshall, Konrad Reinhart eBioMedicine 2016 Apr;6:114-125 DOI: 10.1016/j.ebiom.2016.03.006Download pdf 🡇 Funding The works were supported by the BMBF within the framework of the “MetaZIK”/ZIK Septomics

1 April, 2015

Endotoxemia as a diagnostic tool for patients with suspected bacteremia caused by gram-negative organisms: a meta-analysis of 4 decades of studies

2023-02-16T15:37:11+03:00By hiss|Categories: Biomarkers, Publications|Tags: meta-analysis|

James C Hurley, Piotr Nowak, Lars Öhrmalm, Charalambos Gogos, Apostolos Armaganidis, Evangelos J. Giamarellos-Bourboulis Journal of Clinical Microbiology 2015 Apr;53(4):1183-91 DOI: 10.1128/JCM.03531-14 View article 🡇 FundingThis research was supported by the Australian Government Department of Health and Ageing through the Rural Clinical Training and Support program. Keywords: Endotoxemia; Bacteremia