Publications

1 May, 2021

Differential response induced by LPS and MPLA in immunocompetent and septic individuals

2023-02-16T13:25:47+03:00By hiss|Categories: Publications, Sepsis and severe infections|Tags: clinical trial, Sepsis|

Chloé Albert Vega, Eleni Karakike, François Bartolo, William Mouton, Elisabeth Cerrato, Karen Brengel-Pesce, Evangelos J. Giamarellos-Bourboulis, François Mallet, Sophie Trouillet-Assant Clinical Immunology 2021 May;226:108714 DOI: 10.1016/j.clim.2021.108714 View article 🡇 Funding This work was supported by Marie Sklodowska-Curie Innovative Training H2020-MSCA-ITN-2015, under the grant agreement No 676129. Keywords: Immune functional

1 May, 2021

Immunomodulation Through Beta-D-glucan in Chemically-induced Necrotizing Pancreatitis

2023-02-16T13:26:16+03:00By hiss|Categories: Other Grants, Publications|Tags: PhD|

Nikolaos N Koliakos, Georgios Renieris, Dimitrios Sotiropoulos, Kalliopi Pavlou, Dionysia-Eirini Droggiti, Theologia Gkavogianni, Anestis Charalampopoulos, Evangelos J. Giamarellos-Bourboulis Journal of Surgical Research 2021 May;261:74-84 DOI: 10.1016/j.jss.2020.12.020View article 🡇 Funding This study was funded by the Hellenic Institute for the Study of Sepsis. Keywords: Beta-D-glucan; Immunomodulation; Pancreatitis

1 May, 2021

Staphylococcus aureus Carriage in Hidradenitis Suppurativa: Impact on Response to Adalimumab

2023-02-16T13:26:43+03:00By hiss|Categories: Publications|Tags: Hidradenitis suppurativa|

Dimitra Stergianou, Vassiliki Tzanetakou, Maria Argyropoulou, Theodora Kanni, Pantelis G Bagos, Evangelos J. Giamarellos-Bourboulis Dermatology 2021;237(3):372-377 DOI: 10.1159/000512617 View article 🡇 Keywords: Adalimumab; Carriage; Hidradenitis suppurativa; Response; Staphylococcus aureus

1 April, 2021

Biomarkers in sepsis: can they help improve patient outcome?

2023-02-16T13:27:11+03:00By hiss|Categories: Biomarkers, Publications|Tags: Sepsis|

Kyriazopoulou Evdoxia, Poulakou Garyfallia, Evangelos J. Giamarellos-Bourboulis eBioMedicine 2016 Apr;6:114-125 DOI: 10.1097/QCO.0000000000000707 View article 🡇 Funding The study was funded by the Hellenic Institute for the Study of Sepsis. Keywords: biomarkers; mortality; multidrug-resistant; procalcitonin; sepsis

9 March, 2021

Use of IFNγ/IL10 Ratio for Stratification of Hydrocortisone Therapy in Patients With Septic Shock

2024-04-01T07:14:49+03:00By hiss|Categories: Pathogenesis, Publications|Tags: Sepsis|

Rainer König, Amol Kolte, Olaf Ahlers, Marcus Oswald, Veiko Krauss, Daniela Roell, Oliver Sommerfeld, George Dimopoulos, Iraklis Tsangaris, Eleni Antoniadou, Neeraja Jaishankar, Holger Bogatsch, Markus Löffler, Markus Rödel, Marina Garcia-Moreno, Lorena Tuchscherr, Charles L Sprung, Mervyn Singer, Frank Brunkhorst, Michael Oppert, Herwig Gerlach, Ralf A Claus, Sina M Coldewey, Josef Briegel, Evangelos J. Giamarellos-Bourboulis,

8 March, 2021

An open label trial of anakinra to prevent respiratory failure in COVID-19

2024-03-29T14:13:13+03:00By hiss|Categories: Multicenter studies in Greece, Publications, Therapeutics|Tags: Anakinra, COVID-19, suPAR|

Evdoxia Kyriazopoulou, Periklis Panagopoulos, Symeon Metallidis, George N Dalekos, Garyphallia Poulakou, Nikolaos Gatselis, Eleni Karakike, Maria Saridaki, Georgia Loli, Aggelos Stefos, Danai Prasianaki, Sarah Georgiadou, Olga Tsachouridou, Vasileios Petrakis, Konstantinos Tsiakos, Maria Kosmidou, Vassiliki Lygoura, Maria Dareioti, Haralampos Milionis, Ilias C Papanikolaou, Karolina Akinosoglou, Dimitra-Melia Myrodia, Areti Gravvani, Aliki Stamou, Theologia Gkavogianni, Konstantina Katrini,

1 February, 2021

Validation of Inflammopathic, Adaptive, and Coagulopathic Sepsis Endotypes in Coronavirus Disease 2019

2024-03-29T14:07:31+03:00By hiss|Categories: Publications|Tags: COVID-19, Sepsis|

Timothy E Sweeney, Oliver Liesenfeld, James Wacker, Yudong D He, David Rawling, Melissa Remmel, Sabrina Coyle, Uros Midic, Antigone Kotsaki, Aggeliki Kanavou, Konstantinos Leventogiannis, Ioanna Kontogeorgou, Evangelos J. Giamarellos-Bourboulis Critical Care Medicine 2021 Feb 1;49(2):e170-e178 DOI: 10.1097/CCM.0000000000004786 Download pdf 🡇 Funding Part of the study was funded by the Hellenic Institute

15 January, 2021

Procalcitonin to Reduce Long-Term Infection-associated Adverse Events in Sepsis. A Randomized Trial

2024-03-29T14:03:16+03:00By hiss|Categories: Publications, Therapeutics|Tags: clinical trial, procalcitonin, Sepsis|

Evdoxia Kyriazopoulou, Lydia Liaskou-Antoniou, George Adamis, Antonia Panagaki, Nikolaos Melachroinopoulos, Elina Drakou, Konstantinos Marousis, Georgios Chrysos, Andronikos Spyrou, Nikolaos Alexiou, Styliani Symbardi, Zoi Alexiou, Styliani Lagou, Virginia Kolonia, Theologia Gkavogianni, Miltiades Kyprianou, Ioannis Anagnostopoulos, Garyfallia Poulakou, Malvina Lada, Anna Makina, Efrosyni Roulia, Marina Koupetori, Vasileios Apostolopoulos, Dimitra Petrou, Thomas Nitsotolis, Anastasia Antoniadou, Evangelos J.

13 January, 2021

Disease severity-specific neutrophil signatures in blood transcriptomes stratify COVID-19 patients

2023-02-16T13:35:55+03:00By hiss|Categories: Genetics, Publications|Tags: COVID-19, genetics|

Anna C Aschenbrenner, Maria Mouktaroudi, Benjamin Krämer, Marie Oestreich, Nikolaos Antonakos, Melanie Nuesch-Germano, Konstantina Gkizeli, Lorenzo Bonaguro, Nico Reusch, Kevin Baßler, Maria Saridaki, Rainer Knoll, Tal Pecht, Theodore S Kapellos, Sarandia Doulou, Charlotte Kröger, Miriam Herbert, Lisa Holsten, Arik Horne, Ioanna D Gemünd, Nikoletta Rovina, Shobhit Agrawal, Kilian Dahm, Martina van Uelft, Anna Drews,

1 January, 2021

Diabetes on sepsis outcomes in non-ICU patients: A cohort study and review of the literature

2023-02-16T13:36:16+03:00By hiss|Categories: Biomarkers, Publications|Tags: diabetes, Sepsis|

Karolina Akinosoglou, Georgia Kapsokosta, Maria Mouktaroudi, Nikoletta Rovina, Vassileios Kaldis, Aggelos Stefos, Marina Kontogiorgi, Evangelos J. Giamarellos-Bourboulis, Charalambos Gogos, Hellenic Sepsis Study Group Journal of Diabetes and Its Complications 2021 Jan;35(1):107765 DOI: 10.1016/j.jdiacomp.2020.107765View article 🡇 Funding The works were supported by the BMBF within the framework of the “MetaZIK”/ZIK Septomics Jena (03Z2J521),