Support of publications
Based on its mission, the Hellenic Institute for the Study of Sepsis is supporting three types of publications of manuscripts:
a) manuscripts of the Hellenic Sepsis Study Group;
b) manuscripts on hidradenitis suppurativa; and
c) manuscripts on sepsis.
Support is provided to both pre-clinical and clinical studies and involves the expenses for personnel and consumables.
A list of supported publications is provided below.
The majority of manuscripts published by the Hellenic Sepsis Study Group, are coming from the registry of patients that has started in 2006 and that has been approved by the Ethics Committees of the hospitals (details on Ethical Approval are provided on the Methods section of each manuscript).
The manuscripts are classified by research topic. When the copyright belongs to the authors the entire pdf is given for free or else the manuscript is linked to the PubMed respective site.
Our Library
Early treatment of COVID-19 with anakinra guided by soluble urokinase plasminogen receptor plasma levels: a double-blind, randomized controlled phase 3 trial
Publication in Nature Medicine
Favorable Anakinra Responses in Severe Covid-19 Patients with Secondary Hemophagocytic Lymphohistiocytosis
George Dimopoulos, Quirijn de Mast, Nikolaos Markou, Maria Theodorakopoulou, Apostolos Komnos, Maria Mouktaroudi, Mihai G Netea, Themistoklis Spyridopoulos, Rebecca J Verheggen, Jacobien Hoogerwerf, Alexandra Lachana, Frank L van de Veerdonk, Evangelos J. Giamarellos-Bourboulis Cell Host & Microbe 2020 Jul 8;28(1):117-123.e1 DOI 10.1016/j.chom.2020.05.007Download pdf 🡇 Funding The study was funded in part by the
MABp1 targeting interleukin-1α in hidradenitis suppurativa ineligible for adalimumab treatment: results of the open-label extension period
Theodora Kanni, Maria Argyropoulou, Charles A Dinarello, John Simard, Evangelos J. Giamarellos-Bourboulis Clinical and Experimental Dermatology 2021 Jan;46(1):162-163 DOI: 10.1111/ced.14333 View article 🡇 Funding XBiotech, Texas Hellenic Sepsis Study Group Keywords: Hidradenitis Suppurativa Related Study: HIDRA04
Complex Immune Dysregulation in COVID-19 Patients with Severe Respiratory Failure
Evangelos J. Giamarellos-Bourboulis, Mihai G Netea, Nikoletta Rovina, Karolina Akinosoglou, Anastasia Antoniadou, Nikolaos Antonakos, Georgia Damoraki, Theologia Gkavogianni, Maria-Evangelia Adami, Paraskevi Katsaounou, Maria Ntaganou, Magdalini Kyriakopoulou, George Dimopoulos, Ioannis Koutsodimitropoulos, Dimitrios Velissaris, Panagiotis Koufargyris, Athanassios Karageorgos, Konstantina Katrini, Vasileios Lekakis, Mihaela Lupse, Antigone Kotsaki, George Renieris, Danai Theodoulou, Vassiliki Panou, Evangelia Koukaki, Nikolaos Koulouris,
Trained Immunity: a Tool for Reducing Susceptibility to and the Severity of SARS-CoV-2 Infection
Mihai G Netea, Evangelos J. Giamarellos-Bourboulis, Jorge DomÃnguez-Andrés, Nigel Curtis, Reinout van Crevel, Frank L van de Veerdonk, Marc Bonten Cell 2020 May 28;181(5):969-977 DOI 10.1016/j.cell.2020.04.042 View article 🡇 Funding M.G.N. was supported by an ERC advanced grant (833247) and a Spinoza grant of the Netherlands Association for Scientific Research.
Soluble urokinase plasminogen activator receptor (suPAR) as an early predictor of severe respiratory failure in patients with COVID-19 pneumonia
Nikoletta Rovina, Karolina Akinosoglou, Jesper Eugen-Olsen, Salim Hayek, Jochen Reiser, Evangelos J. Giamarellos-Bourboulis Critical Care 2020 Apr 30;24(1):187 DOI: 10.1186/s13054-020-02897-4View article 🡇 Funding The study was funded by unrestricted educational grants provided by the Hellenic Institute for the Study of Sepsis. Funds were also provided by Rush University Medical Center. Keywords: COVID-19;
Association of modulation of pro-inflammatory responses by dectin-2 with preterm delivery: An experimental model
Aspasia Liassidou, Georgios Renieris, Dionysia-Irene Droggiti, Theologia Gkavogianni, Christakis Liassides, Labros Sabracos, Evangelos J. Giamarellos-Bourboulis, Charalampos S Siristatidis American Journal of Reproductive Immunology 2020 Mar;83(3):e13216 DOI 10.1111/aji.13216 View article 🡇 Keywords: dectin-2; infection; lipopolysaccharide; miscarriage; preterm delivery