Completed study Official Study Title a SUPar guided doublE-blind Randomized clinical trial of Initiation Of antibiotics foR presumed infection at the emergency department Brief Description SUPERIOR is a randomized clinical trial aiming to evaluate suPAR - guided medical intervention, consisting of early antibiotic administration at the emergency room for presumed infection and sepsis and
Karolina Akinosoglou, Spyridoula Theodoraki, Theologia Gkavogianni, Aikaterini Pistiki, Evangelos J. Giamarellos-Bourboulis, Charalambos A Gogos Cytokine 2018 Oct;110:288-290 DOI: 10.1016/j.cyto.2018.01.019View article 🡇 Funding The study was funded by the Hellenic Institute for the Study of Sepsis. Keywords: Anti-inflammatory mediators; Pro-inflammatory mediators; SIRS; Sepsis; qSOFA
Christian Krautz, Sarah L Maier, Maximilian Brunner, Melanie Langheinrich, Evangelos J. Giamarellos-Bourboulis, Charalambos Gogos, Apostolos Armaganidis, Frank Kunath, Robert Grützmann, Georg F Weber Journal of Critical Care 2018 Jun;45:71-75 DOI: 10.1016/j.jcrc.2018.01.013 View article 🡇 Keywords: Circulating B cells; Plasma IgM; Sepsis; Sepsis outcome
Dimitrios Sinapidis, Vassileios Kosmas, Vasileios Vittoros, Ioannis M. Koutelidakis, Aikaterini Pantazi, Aggelos Stefos, Konstantinos E. Katsaros, Karolina Akinosoglou, Magdalini Bristianou, Konstantinos Toutouzas, Michael Chrisofos and Evangelos J. Giamarellos-Bourboulis BMC Infectious Diseases, May 2018 DOI 10.1186/s12879-018-3156-zDownload pdf 🡇 Funding The study was funded by the Hellenic Institute for the Study of Sepsis.
Gabriela Gainaru, Antonios Papadopoulos, Iraklis Tsangaris, Malvina Lada, Evangelos J. Giamarellos-Bourboulis, Aikaterini Pistiki Critical Care 2018 Mar 3;22(1):56 DOI: 10.1186/s13054-018-1977-1View article 🡇 Funding The study was funded by the Hellenic Institute for the Study of Sepsis. Keywords: Gram-negative; Inflammatory monocytes; Patrolling monocytes; Sepsis; Survival
Theodoros Retsas, Klaus Huse, Lazaros-Dimitrios Lazaridis, Niki Karampela, Michael Bauer, Matthias Platzer, Virginia Kolonia, Eirini Papageorgiou, Evangelos J. Giamarellos-Bourboulis, George Dimopoulos International Journal of Infectious Diseases 2018 Feb;67:102-106 DOI: 10.1016/j.ijid.2017.12.008Download pdf 🡇 FundingThe study was funded in part by the Hellenic Institute for the Study of Sepsis and by the Federal Ministry of
Completed study Official Study Title A Personalized Randomized Trial of Validation and Restoration of Immune Dysfunction in Severe Infections and Sepsis (PROVIDE) Brief Description PROVIDE is a randomized clinical trial aiming to the personalized therapy of patients at septic shock. Using biomarkers, enrolled patients are randomized through a double-dummy approach to immunotherapy or placebo
Completed study Official Study Title A double-blind, randomized, placebo-controlled clinical study of the efficacy of INtravenous CLArithromycin as adjunctive treatment in patients with Sepsis and respiratory and multiple organ dysfunction Syndrome Brief Description INCLASS is a randomized clinical trial aiming to compare the efficacy of intravenous clarithromycin over placebo in patients with sepsis and
Karolina Akinosoglou, Spyridoula Theodoraki, Ioanna Xanthopoulou, Angelos Perperis, Theologia Gkavogianni, Aikaterini Pistiki, Evangelos J Giamarellos-Bourboulis, Charalambos A Gogos European Journal of Clinical Microbiology & Infectious Diseases 2017 Dec;36(12):2503-2512 DOI: 10.1007/s10096-017-3093-6View the article 🡇 Funding This work was funded by the Hellenic Institute for the Study of Sepsis. Keywords: Organ dysfunction; P2Y12 platelet
S Christodoulou, E Kyriazopoulou, M Chrysanthakopoulou, G Karlis, I Karampela, K Gkizeli, N Veliki, A Safarika, E J Giamarellos-Bourboulis, G Adamis; Hellenic Sepsis Study Group European Journal of Clinical Microbiology & Infectious Diseases 2017 Nov;36(11):2171-2177 DOI: 10.1007/s10096-017-3041-5View article 🡇 Funding The study was funded by the Hellenic Institute for the Study of Sepsis.